ArticleMedical physics2010
Electron paramagnetic resonance oxygen imaging of a rabbit tumor using localized spin probe delivery.
Article in Medical physics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 50 citations in OpenAlex.
- Accelerated EPR imaging using deep learning denoising.Magnetic resonance in medicine · 2025Article
- Celebration of 80 years of EPR.Applied magnetic resonance · 2024Article
- Oxygen Imaging of a Rabbit Tumor Using a Human-Sized Pulse Electron Paramagnetic Resonance Imager.Molecular imaging and biology · 2024Article
- Evaluating Tumor Hypoxia Radiosensitization Via Electron Paramagnetic Resonance Oxygen Imaging (EPROI).Molecular imaging and biology · 2024Article
- Assessment of blood-brain barrier leakage and brain oxygenation in Connexin-32 knockout mice with systemic neuroinflammation using pulse electron paramagnetic resonance imaging techniques.Magnetic resonance in medicine · 2024Article
- Nondestructive, longitudinal, 3D oxygen imaging of cells in a multi-well plate using pulse electron paramagnetic resonance imaging.Npj imaging · 2024Article
- In vitro oxygen imaging of acellular and cell-loaded beta cell replacement devices.Scientific reports · 2023Article
- Synthesis and characterization of a biocompatibleThe Analyst · 2022Article
- An iterative reconstruction algorithm without system matrix for EPR imaging.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2022Article
- Dual-Mode Tumor Imaging Using Probes That Are Responsive to Hypoxia-Induced Pathological Conditions.Biosensors · 2022Review
- Article
- Ox-SLIM: Synthesis of and Site-Specific Labelling with a Highly Hydrophilic Trityl Spin Label.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Article
- Biological validation of electron paramagnetic resonance (EPR) image oxygen thresholds in tissue.The Journal of physiology · 2021Review
- Improved, Odorless Access to Benzo[1,2-d;4,5-d']- bis[1,3]dithioles andMolecules (Basel, Switzerland) · 2020Article
- SLIM: A Short-Linked, Highly Redox-Stable Trityl Label for High-Sensitivity In-Cell EPR Distance Measurements.Angewandte Chemie (International ed. in English) · 2020Article
- Merging Preclinical EPR Tomography with other Imaging Techniques.Cell biochemistry and biophysics · 2019Article
- Tabletop 700 MHz electron paramagnetic resonance imaging spectrometer.Concepts in magnetic resonance. Part B, Magnetic resonance engineering · 2018Article
- Resonators for In Vivo Imaging: Practical Experience.Applied magnetic resonance · 2017Article
- In vivo preclinical cancer and tissue engineering applications of absolute oxygen imaging using pulse EPR.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2017Review
- Fast dynamic electron paramagnetic resonance (EPR) oxygen imaging using low-rank tensors.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
purposeApplication of in vivo electron paramagnetic resonance (EPR) oxygen imaging (EPROI) to tumors larger than those of mice requires development of both instrumental and medical aspects of imaging.
methods250 MHz EPR oxygen imaging was performed using a loop-gap resonator with a volume exceeding 100 cm3. The paramagnetic spin probe was injected directly into the femoral artery feeding the rabbit leg/tumor.
resultsThe authors present continuous wave and electron spin echo EPR oxygen images of a large size (4 cm) VX-2 tumor located on the leg of a New Zealand white rabbit.
conclusionsThis study demonstrates the feasibility of continuous wave and electron spin echo oxygen imaging modalities for investigation of volumes of tumor and normal tissue relevant to large animals. The injection of the spin probe directly into the artery feeding a rabbit leg will allow one to reduce, by over one order of magnitude, the amount of spin probe used as compared to whole animal i.v. injection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.