Evidence map›Paper›PMID 20632209›Full record

ArticleMycopathologia2011

Differential resistance to oxidants and production of hydrolytic enzymes in Candida albicans.

Maxwel A Abegg, Rodrigo Lucietto, Paulo V G Alabarse, Marcus F A Mendes, Mara Silveira Benfato

Abstract read
PubMed Publisher
In one paragraph

Article in Mycopathologia, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Journal of oral microbiology · 2020
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Maxwel A AbeggUniversidade Paranaense, UNIPAR, Toledo, PR, Brazil.
Rodrigo Lucietto
Paulo V G Alabarse
Marcus F A Mendes
Mara Silveira Benfato
Universidade Federal do Rio Grande do Sul · BRUniversidade Paranaense · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resistance to the toxic effects of reactive oxygen species produced by phagocytes and production of hydrolytic enzymes are important aspects of Candida albicans virulence. In this report, we compared twelve C. albicans isolates for their in vitro capacity to resist oxidants-hydrogen peroxide, menadione and paraquat; and to produce hydrolytic enzymes-phospholipase and protease. Different C. albicans isolates showed different degrees of resistance to oxidants as well as differences in production of hydrolytic enzymes. Resistance to oxidative stress did not correlate with production of hydrolytic enzymes. This reinforces the view that C. albicans differentially regulates the expression of virulence factors in response to local environmental conditions.

Indexed as

Drug Resistance, FungalAntifungal AgentsCandida albicansEnzymesFungal ProteinsHydrogen PeroxideHydrolysisMicrobial Sensitivity TestsOxidantsParaquatVitamin K 3Antifungal AgentsEnzymesFungal ProteinsHydrogen PeroxideOxidantsParaquatVitamin K 3

Identifiers

PMID20632209
OpenAlexW1982077614

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.