ArticleMolecular biology reports2011
Gamma radiation induced mutagenesis in Aspergillus niger to enhance its microbial fermentation activity for industrial enzyme production.
Article in Molecular biology reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 54 citations in OpenAlex.
- Optimization of fermentation parameters and mutagenesis of Glarea lozoyensis ATCC 20868 towards pneumocandin BBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Statistical optimization and gamma irradiation on cephalosporin C production by Acremonium chrysogenum W42-I.AMB Express · 2023Article
- Gamma irradiation mediated production improvement of some myco-fabricated nanoparticles and exploring their wound healing, anti-inflammatory and acetylcholinesterase inhibitory potentials.Scientific reports · 2023Article
- Bioprospecting endophytic fungi for antifeedants and larvicides and their enhancement by gamma irradiation.AMB Express · 2022Article
- Exploiting the exceptional biosynthetic potency of the endophyticSaudi journal of biological sciences · 2022Article
- Article
- Development of One Pot Strategy for Hyper Production and In Vivo Evaluation of Lovastatin.Molecules (Basel, Switzerland) · 2020Article
- Enhanced production of lipstatin from mutant of3 Biotech · 2020Article
- Overproduction of Glucose Oxidase byBioMed research international · 2020Article
- Random mutagenesis of super Koji (Aspergillus oryzae): improvement in production and thermal stability of α-amylases for maltose syrup production.BMC microbiology · 2018Article
- Potential role of the common food additive manufactured citric acid in eliciting significant inflammatory reactions contributing to serious disease states: A series of four case reports.Toxicology reports · 2018Article
- Article
- Application of radiation technology in vaccines development.Clinical and experimental vaccine research · 2015Review
- The effect of gamma irradiation on astaxanthin synthetase encoding gene in two mutant strains of Phaffia rhodozyma.Iranian journal of microbiology · 2013Article
- Genetic diversity and effect of temperature and pH on the growth of Macrophomina phaseolina isolates from sunflower fields in Hungary.Molecular biology reports · 2012Article
- Characterization of Malaysian Trichoderma isolates using random amplified microsatellites (RAMS).Molecular biology reports · 2012Article
- Impact of gamma rays on the Phaffia rhodozyma genome revealed by RAPD-PCR.Iranian journal of microbiology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
α- and β-Galactosidases find application in food processing, health and nutrition. Aspergillus niger is one of the potent producer of these enzymes and was genotypically improved using gamma-ray induced mutagenesis. The mutant-derivative produced two-fold higher α- and β-galactosidases. For testing genetic variability and its relationship with phenotypic properties of the two organisms, DNA samples of the mutant and parental strains of A. niger were amplified with 28 deca-nucleotide synthetic primers. RAPD analysis showed significantly different pattern between parental and mutant cultures. The mutant derivative yielded homogeneous while parental strain formed heterogeneous amplification patterns. Seven primers identified 42.9% polymorphism in the amplification products, indicating that these primers determined some genetic variability between the two strains. Thus RAPD was found to be an efficient technique to determine genetic variability in the mutant and wild organisms. Both wild and mutant strains were analyzed for their potential to produce galactosidases. Comparison of different carbon sources on enzyme yield revealed that wheat bran is significant (P < 0.01) effective producer and economical source followed by rice bran, rice polishing and lactose. The mutant was significantly better enzyme producer and could be considered for its prospective application in food, nutrition and health and that RAPD can be effectively used to differentiate mutant strain from the parental strain based on the RAPD patterns.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.