Evidence map›Paper›PMID 20632103›Full record

ReviewDigestive diseases and sciences2010

Proteomic analyses lead to a better understanding of celiac disease: focus on epitope recognition and autoantibodies.

Valli De Re, Maria Paola Simula, Vincenzo Canzonieri, Renato Cannizzaro

Abstract readReview
PubMed Publisher
In one paragraph

Review in Digestive diseases and sciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Protein-protein interaction network of celiac disease.Gastroenterology and hepatology from bed to bench · 2016
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Valli De ReExperimental and Clinical Pharmacology Unit, Molecular Oncology and Translational Medicine, Domert, Centro di Riferimento Oncologico, IRCCS National Cancer Institute, via F. Gallini 2, Aviano, PN, Italy. vdere@cro.it
Maria Paola Simula
Vincenzo Canzonieri
Renato Cannizzaro
Centro di Riferimento Oncologico · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITNational Cancer Institute · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proteomic technologies are being used with increasing frequency in the scientific community. In this review, we have highlighted their use in celiac disease (CD). The available techniques, which include two-dimensional (2D) gel electrophoresis, mass spectrometry, and antibody and tissue arrays, have been used to identify proteins or changes in protein expression specific to gut tissue from patients with CD. A number of studies have employed proteomic methodologies to determine the diagnostic biomarkers in body fluids or to examine changes in protein expression and posttranslational modifications during signaling. A fast technological development of these methods, along with the combination of classic techniques with proteomics, will lead to new discoveries, which will consent a better understanding of the pathogenesis of CD.

Indexed as

AutoantibodiesCeliac DiseaseCytochrome P-450 Enzyme SystemElectrophoresis, Gel, Two-DimensionalEpitope MappingGTP-Binding ProteinsHumansMass SpectrometryProtein Array AnalysisProtein Glutamine gamma Glutamyltransferase 2ProteomicsTissue Array AnalysisTransglutaminasesAutoantibodiesCytochrome P-450 Enzyme SystemGTP-Binding ProteinsProtein Glutamine gamma Glutamyltransferase 2Transglutaminases

Identifiers

PMID20632103
OpenAlexW2064633033

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.