Evidence map›Paper›PMID 20631494›Full record

ReviewJournal of endocrinological investigation2010

Hormones and antioxidant systems: role of pituitary and pituitary-dependent axes.

A Mancini, R Festa, V Di Donna, E Leone, G P Littarru, A Silvestrini, E Meucci, A Pontecorvi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of endocrinological investigation, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Total Antioxidant Capacity: Biochemical Aspects and Clinical Significance.International journal of molecular sciences · 2023
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Effect of Ubiquinol on Serum Reproductive Hormones of Amenorrhic Patients.Indian journal of clinical biochemistry : IJCB · 2016
    Article
  15. Effects ofFood science and biotechnology · 2016
    Article
  16. Review
  17. Review
  18. Article
  19. Hormonal influence on coenzyme Q(10) levels in blood plasma.International journal of molecular sciences · 2011
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

A ManciniDepartment of Internal Medicine, Catholic University of the Sacred Heart, Rome, Italy. mancini.giac@mclink.it
R Festa
V Di Donna
E Leone
G P Littarru
A Silvestrini
E Meucci
A Pontecorvi
University of the Sacred Heart · JPUniversità Cattolica del Sacro Cuore · ITMarche Polytechnic University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress, a condition defined as unbalancing between production of free radicals and antioxidant defenses, is an important pathogenetic mechanism in different diseases. Despite the abundant literature, many aspects of hormone role in regulating antioxidant synthesis and activity still remain obscure. Therefore, we reviewed experimental data, in vivo and in vitro, about the effects of the different pituitary- dependent axes on antioxidant levels, trying to give a broad view from hormones which also have antioxidant properties to the classic antioxidants, from the lipophilic antioxidant Coenzyme Q10, strictly related to thyroid function, to total antioxidant capacity, a measure of non-protein non-enzymatic antioxidants in serum and other biological fluids. Taken together, these data underline the importance of oxidative stress in various pituitary-dependent disorders, suggesting a possible clinical usefulness of antioxidant molecules.

Indexed as

AnimalsAntioxidantsEstradiolFemaleGonadsGrowth HormoneHumansMaleOxidative StressPituitary-Adrenal SystemPituitary GlandProlactinTestosteroneThyroid GlandUbiquinoneAntioxidantsEstradiolGrowth HormoneProlactinTestosteroneUbiquinone

Identifiers

PMID20631494
OpenAlexW2040436007

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.