ReviewSeminars in immunology2010
Molecular and cellular basis of T cell lineage commitment.
Review in Seminars in immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Induction of Thymus Atrophy and Disruption of Thymocyte Development by Fipronil through Dysregulation of IL-7-Associated Genes.Chemical research in toxicology · 2024Article
- Flow Cytometric Identification of Hematopoietic and Leukemic Blast Cells for Tailored Clinical Follow-Up of Acute Myeloid Leukemia.International journal of molecular sciences · 2022Review
- Exploring the stage-specific roles of Tcf-1 in T cell development and malignancy at single-cell resolution.Cellular & molecular immunology · 2021Article
- Phosphate Transporter Profiles in Murine and Human Thymi Identify Thymocytes at Distinct Stages of Differentiation.Frontiers in immunology · 2020Article
- Producing proT cells to promote immunotherapies.International immunology · 2018Review
- Novel tumor-suppressor function of KLF4 in pediatric T-cell acute lymphoblastic leukemia.Experimental hematology · 2017Review
- Thymus transcriptome reveals novel pathways in response to avian pathogenic Escherichia coli infection.Poultry science · 2016Article
- Establishment and Maintenance of the Human Naïve CD4Frontiers in pediatrics · 2016Review
- Forging T-Lymphocyte Identity: Intersecting Networks of Transcriptional Control.Advances in immunology · 2016Review
- Article
- New insights into IL-7 signaling pathways during early and late T cell development.Cellular & molecular immunology · 2013Article
- Analysis of Rho GTPase expression in T-ALL identifies RhoU as a target for Notch involved in T-ALL cell migration.Oncogene · 2013Article
- Cellular and population plasticity of helper CD4(+) T cell responses.Frontiers in physiology · 2013Article
- Cytokines of the γ(c) family control CD4+ T cell differentiation and function.Nature immunology · 2012Review
- High levels of IL-7 cause dysregulation of thymocyte development.International immunology · 2012Article
- Intrathymic IL-7: the where, when, and why of IL-7 signaling during T cell development.Seminars in immunology · 2012Review
- Identification of the earliest natural killer cell-committed progenitor in murine bone marrow.Blood · 2011Article
- Article
- Review
- Molecular and cellular basis of T cell lineage commitment: An overview.Seminars in immunology · 2010Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
The thymus forms as an alymphoid thymic primordium with T cell differentiation requiring the seeding of this anlage. This review will focus on the characteristics of the hematopoietic progenitors which colonize the thymus and their subsequent commitment/differentiation, both in mice and men. Within the thymus, the interplay between Notch1 and IL-7 signals is crucial for the orchestration of T cell development, but the precise requirements for these factors in murine and human thympoeisis are not synonymous. Recent advances in our understanding of the mechanisms regulating precursor entry and their maintenance in the thymus will also be presented.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.