ArticleJournal of clinical hypertension (Greenwich, Conn.)2010
Assessment of endothelial function by means of flow-mediated changes using pulse wave velocity.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Article
- Endothelium function dependence of acute changes in pulse wave velocity and flow-mediated slowing.Vascular medicine (London, England) · 2020Article
- Flow-Mediated Slowing as a Methodological Alternative to the Conventional Echo-Tracking Flow-Mediated Dilation Technique for the Evaluation of Endothelial Function: A Preliminary Report.Mayo Clinic proceedings. Innovations, quality & outcomes · 2018Article
- The association between arterial stiffness and carotid intima-media thickness in patients with known cardiovascular risk factors.Clujul medical (1957) · 2013Article
- Hyperemia-Related Changes in Arterial Stiffness: Comparison between Pulse Wave Velocity and Stiffness Index in the Vascular Reactivity Assessment.International journal of vascular medicine · 2012Article
- An innovative piezoelectric-based method for measuring pulse wave velocity in patients with hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2011Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endothelial dysfunction is a leading cause of early development of cardiovascular diseases. Endothelial function can be assessed using ultrasound methods to watch the arterial flow-mediated dilation. It is also possible to find changes in pulse wave velocity (PWV) after induced ischemia related to the vessel diameter changes. Pre- and post-induced ischemia carotid-radial PWV was recorded in 226 hypertensive patients (150 women [63.5+/-12.4 years old] and 76 men [63.2+/-11.8 years old] and 55 healthy patients (38 women [63.1+/-12.6 years old] and 17 men [54.8+/-12.8 years old]). The authors considered normal endothelial function a PWV reduction of 5% from baseline. To assess nondependent endothelial dilation the authors performed carotid-radial PWV after sublingual administration of 5 mg of isosorbide dinitrate in a group of patients with abnormal flow-mediated dilation. A significant PWV reduction of 9.8% in normal patients and only 1.2% among hypertensive patients (P<.0005) was found. After sublingual isosorbide dinitrate intake the authors observed a greater fall in PWV (14%) than that observed in healthy people after induced ischemia. Carotid-radial PWV after induced ischemia decreased significantly in normal participants. No significant changes were observed in hypertensive patients. These results may offer a reliable tool to assess endothelial function in medium-size arteries.
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