ArticleNeuropsychiatric disease and treatment2010
Tinnitus psychopharmacology: A comprehensive review of its pathomechanisms and management.
Article in Neuropsychiatric disease and treatment, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 44 citations in OpenAlex.
- Distribution of Metabotropic Serotonin Receptors in GABAergic and Glutamatergic Neurons in the Auditory Midbrain.The Journal of comparative neurology · 2026Article
- Mindfulness-based therapy for chronic tinnitus: a narrative review.Frontiers in psychology · 2026Review
- A retrospective two-center cohort study of the bidirectional relationship between depression and tinnitus-related distress.Communications medicine · 2024Article
- The impact of tinnitus on Dutch general practices: A retrospective study using routine healthcare data.PloS one · 2024Article
- The association between stress, emotional states, and tinnitus: a mini-review.Frontiers in aging neuroscience · 2023Review
- Effect of Tinnitus in Distortion Products Otoacoustic Emissions (DPOAEs) in Normal Hearing Patients.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022Article
- Complex auditory musical hallucinations with ambivalent feelings.BMJ case reports · 2021Article
- Review of Pharmacotherapy for Tinnitus.Healthcare (Basel, Switzerland) · 2021Review
- The Mediating Effect of Psychological Distress on the Association between BDNF, 5-HTTLPR, and Tinnitus Severity.Psychiatry investigation · 2021Article
- Approach to tinnitus management.Canadian family physician Medecin de famille canadien · 2018Review
- Review
- Tinnitus: The Sound of Stress?Clinical practice and epidemiology in mental health : CP & EMH · 2018Article
- Serotonergic regulation of excitability of principal cells of the dorsal cochlear nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Coexistence of anxiety sensitivity and psychiatric comorbidities in patients with chronic tinnitus.Neuropsychiatric disease and treatment · 2015Article
- Evaluation of distortion and transient evoked otoacoustic emission in tinnitus patients with normal hearing.Iranian journal of otorhinolaryngology · 2014Article
- A brain centred view of psychiatric comorbidity in tinnitus: from otology to hodology.Neural plasticity · 2014Review
- Vascular loop in the cerebellopontine angle causing pulsatile tinnitus and headache: a case report.EXCLI journal · 2014Article
- Evaluation of anxiety and depressive levels in tinnitus patients.Korean journal of audiology · 2013Article
- Is there any predictor for tinnitus outcome in different types of otologic surgery?European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2013Article
- Betahistine in the treatment of tinnitus in patients with vestibular disorders.Brazilian journal of otorhinolaryngologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSubjective tinnitus is a frequent, impairing condition, which may also cause neurotransmitter imbalance at the cochlea. Psychopharmacologic agents, although not being the first-line treatment for tinnitus, may modulate cochlear neurotransmission, thereby influencing the subjective tinnitus experience.
methodA comprehensive review of MEDLINE literature (from January 1990-January 2010) was performed searching for: "tinnitus", major classes of psychopharmacological agents, and psychiatric disorders. The most relevant clinical evidence is reported briefly along with a concise description of the main neurotransmitters purported to be involved in tinnitus, in order to provide the reader with a rational evaluation of tinnitus therapy with psychopharmacological agents.
resultsAlthough strong methodological issues limit the reliability of the current results, a broad number of psychopharmacological agents have already been considered for tinnitus, both as candidate triggers or potential therapies.
conclusionsSelected psychopharmacological drugs may play a role in the clinical management of this disorder. While the rational use of these agents for the treatment of tinnitus should not be overlooked, research should be undertaken on their neuromodulating actions at the cochlea.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.