ReviewNature reviews. Gastroenterology & hepatology2010
The role of radiotherapy in locally advanced pancreatic carcinoma.
Review in Nature reviews. Gastroenterology & hepatology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Intensity modulated radiotherapy for locally advanced and metastatic pancreatic cancer: a mono-institutional retrospective analysis.Radiation oncology (London, England) · 2015Trial
- Extracellular volume-based scoring system for tracking tumor progression in pancreatic cancer patients receiving intraoperative radiotherapy.Insights into imaging · 2024Article
- The application of a three-dimensional visualized seed planning and navigation system inOncoTargets and therapy · 2018Article
- Increased expression of calponin 2 is a positive prognostic factor in pancreatic ductal adenocarcinoma.Oncotarget · 2017Article
- CD44Oncology letters · 2017Article
- Focal Radiation Therapy Dose Escalation Improves Overall Survival in Locally Advanced Pancreatic Cancer Patients Receiving Induction Chemotherapy and Consolidative Chemoradiation.International journal of radiation oncology, biology, physics · 2016Article
- Nanog Predicts Poor Prognosis in Human Pancreatic Cancer and Is Downregulated by QingyihuaJi Formula in Pancreatic Cancer Stem Cells.Evidence-based complementary and alternative medicine : eCAM · 2016Article
- Phase I Trial of Consolidative Radiotherapy with Concurrent Bevacizumab, Erlotinib and Capecitabine for Unresectable Pancreatic Cancer.PloS one · 2016Article
- Rare long-term survivors of pancreatic adenocarcinoma without curative resection.World journal of gastroenterology · 2015Article
- Inhibition of glutamine metabolism counteracts pancreatic cancer stem cell features and sensitizes cells to radiotherapy.Oncotarget · 2015Article
- Technical advances in endoscopic ultrasound-guided fiducial placement for the treatment of pancreatic cancer.Endoscopy international open · 2015Review
- Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery.Cancer research · 2015Article
- Antibody against CD44s inhibits pancreatic tumor initiation and postradiation recurrence in mice.Gastroenterology · 2014Article
- Segmentation precision of abdominal anatomy for MRI-based radiotherapy.Medical dosimetry : official journal of the American Association of Medical Dosimetrists · 2014Article
- The investigation of 125I seed implantation as a salvage modality for unresectable pancreatic carcinoma.Journal of experimental & clinical cancer research : CR · 2013Article
- miR-99b-targeted mTOR induction contributes to irradiation resistance in pancreatic cancer.Molecular cancer · 2013Article
- Radiation dose ≥54 Gy and CA 19-9 response are associated with improved survival for unresectable, non-metastatic pancreatic cancer treated with chemoradiation.Radiation oncology (London, England) · 2012Article
- K-Ras mutation-mediated IGF-1-induced feedback ERK activation contributes to the rapalog resistance in pancreatic ductal adenocarcinomas.Cancer letters · 2012Article
- Personalized medicine in pancreatic cancer: prognosis and potential implications for therapy.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2012Article
- Genetic effects and modifiers of radiotherapy and chemotherapy on survival in pancreatic cancer.Pancreas · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prognosis for locally advanced pancreatic carcinoma remains dismal despite advances in chemotherapy and radiotherapy over the past few decades. The use of radiotherapy for pancreatic carcinoma is often disputed because of the hypothesis that patients with pancreatic cancer die from distant metastases. It is well accepted that the greatest chance for cure of pancreatic cancer involves surgical resection of the primary tumor. However, there is much controversy about the role of radiotherapy in local disease control. The aim of this Review is to discuss data from the available studies, both prospective and retrospective, that evaluate treatment options for locally advanced pancreatic cancer. We focus on the benefits associated with local therapies, including radiotherapy and surgical resection, as they relate to improved local disease control, prolonged overall survival and improved symptom control.
Indexed as
Identifiers
20628346What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.