Evidence map›Paper›PMID 20627172›Full record

ArticleMethods in enzymology2010

Analysis of single nucleic acid molecules with protein nanopores.

Giovanni Maglia, Andrew J Heron, David Stoddart, Deanpen Japrung, Hagan Bayley

Abstract read
In one paragraph

Article in Methods in enzymology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed.

  1. Article
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  5. Blobs form during the single-file transport of proteins across nanopores.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Mobile Molecules: Reactivity Profiling Guides Faster Movement on a Cysteine Track.Angewandte Chemie (Weinheim an der Bergstrasse, Germany) · 2023
    Article
  13. Mobile Molecules: Reactivity Profiling Guides Faster Movement on a Cysteine Track.Angewandte Chemie (International ed. in English) · 2023
    Article
  14. Nanopore Detection Assisted DNA Information Processing.Nanomaterials (Basel, Switzerland) · 2022
    Review
  15. Article
  16. Methods for isolating and analyzing physiological hyaluronan: a review.American journal of physiology. Cell physiology · 2022
    Review
  17. Article
  18. Article
  19. Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Giovanni MagliaDepartment of Chemistry, University of Oxford, Oxford, United Kingdom.
Andrew J Heron
David Stoddart
Deanpen Japrung
Hagan Bayley

Funding

Single-Molecule DNA Sequencing with Engineered NanoporesR01HG003709 · NHGRI · SCRIPPS RESEARCH INSTITUTE, THE · PI GHADIRI, M. REZA · 2005 to 2017
$13.2M
NHGRI NIH HHS R01 HG003709
6 · The paper itself

Abstract

We describe the methods used in our laboratory for the analysis of single nucleic acid molecules with protein nanopores. The technical section is preceded by a review of the variety of experiments that can be done with protein nanopores. The end goal of much of this work is single-molecule DNA sequencing, although sequencing is not discussed explicitly here. The technical section covers the equipment required for nucleic acid analysis, the preparation and storage of the necessary materials, and aspects of signal processing and data analysis.

Indexed as

NanotechnologyNucleic AcidsPorosityProteinsNucleic AcidsProteins

Identifiers

PMID20627172
PMCPMC3137938

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.