ReviewHead and neck pathology2010
Molecular and clinicopathological findings in a tonsillar synovial sarcoma. A case study and review of the literature.
Review in Head and neck pathology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 14 citations in OpenAlex.
- Biphasic Synovial Sarcoma of the Palatine Tonsil: A Case Report and Literature Review.Clinical case reports · 2025Article
- Tonsillar synovial sarcoma, unusual anatomical location: case report and literature review.Diagnostic pathology · 2024Review
- Pediatric Tonsillar Synovial Sarcoma- Very Rare Localization: A Case Report and Review of the Literature.Turk patoloji dergisi · 2020Review
- Synovial sarcoma oropharynx - a case report and review of literature.Indian journal of surgical oncology · 2014Article
- Primary monophasic synovial sarcoma of the tonsil: immunohistochemical and molecular study of a case and review of the literature.Head and neck pathology · 2013Review
- Synovial sarcoma of the mandible.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2012Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Synovial sarcoma (SS), 3-5% of which occurs in the head and neck region, has generally been regarded as high grade sarcoma. Recent analysis of clinical, morphological, and molecular characteristics of SS, however, identified low and high risk group of patients, resulting in important implications for the treatment of patients diagnosed with SS. We describe the case of a 31-year-old male who presented with biphasic SS with poorly differentiated areas (clinical stage IIA) in a palatine tonsil, an extremely rare site of SS. Molecular analyses revealed typical t(X;18) translocation of the SYT gene and a SYT/SSX1 fusion type. The tumor was surgically resected with free margins. Adjuvant radiotherapy or chemotherapy was not considered indicated. To date, the patient has remained free of tumor for 4 years after surgery. Literature review reveals that primary tonsillar HNSS has previously been documented only in three patients. In all of these patients the tumor was histologically biphasic; however only one published case and the case presented here showed areas of poor differentiation. We discuss the relevance of the presented findings with regard to prognostic and therapeutic considerations in SS in the head and neck region.
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