ReviewStem cell reviews and reports2010
G-protein coupled receptors in stem cell self-renewal and differentiation.
Review in Stem cell reviews and reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- GPCRs as key regulators in wound healing.Frontiers in cell and developmental biology · 2026Review
- The Gα GOA-1/GNAO1 non-autonomously promotes germline stem cell quiescence in feminizedmicroPublication biology · 2026Article
- GPCR Screening Reveals that the Metabolite Receptor HCAR3 Regulates Epithelial Proliferation, Migration, and Cellular Respiration.The Journal of investigative dermatology · 2024Article
- Article
- NPY1R exerts inhibitory action on estradiol-stimulated growth and predicts endocrine sensitivity and better survival in ER-positive breast cancer.Scientific reports · 2022Article
- WDR36 Safeguards Self-Renewal and Pluripotency of Human Extended Pluripotent Stem Cells.Frontiers in genetics · 2022Article
- Activation of G-Protein Coupled Receptor-Gαi Signaling Increases Keratinocyte Proliferation and Reduces Differentiation, Leading to Epidermal Hyperplasia.The Journal of investigative dermatology · 2020Article
- Identification of lncRNAs by RNA Sequencing Analysis DuringFrontiers in genetics · 2019Article
- S1P promotes migration, differentiation and immune regulatory activity in amniotic-fluid-derived stem cells.European journal of pharmacology · 2018Article
- Endothelial progenitor cells: Exploring the pleiotropic effects of statins.World journal of cardiology · 2017Review
- PAR1 Scaffolds TGFβRII to Downregulate TGF-β Signaling and Activate ESC Differentiation to Endothelial Cells.Stem cell reports · 2016Article
- Progressive osseous heteroplasia: diagnosis, treatment, and prognosis.The application of clinical genetics · 2015Review
- G-protein Coupled Receptor Signaling in Pluripotent Stem Cell-derived Cardiovascular Cells: Implications for Disease Modeling.Frontiers in cell and developmental biology · 2015Review
- Somatostatin receptor type 2 contributes to the self-renewal of murine embryonic stem cells.Acta pharmacologica Sinica · 2014Article
- MiR-153 targets the nuclear factor-1 family and protects against teratogenic effects of ethanol exposure in fetal neural stem cells.Biology open · 2014Article
- A genome-wide RNAi screen reveals a Trio-regulated Rho GTPase circuitry transducing mitogenic signals initiated by G protein-coupled receptors.Molecular cell · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stem cells have great potential for understanding early development, treating human disease, tissue trauma and early phase drug discovery. The factors that control the regulation of stem cell survival, proliferation, migration and differentiation are still emerging. Some evidence now exists demonstrating the potent effects of various G-protein coupled receptor (GPCR) ligands on the biology of stem cells. This review aims to give an overview of the current knowledge of the regulation of embryonic and somatic stem cell maintenance and differentiation by GPCR ligands.
Indexed as
Identifiers
20625855What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.