ArticleJournal of neurology2010
Factors associated with long-term functional outcomes and psychological sequelae in Guillain-Barre syndrome.
Article in Journal of neurology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 5 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 5 syntheses or guidelines pooled it, 66 citations in OpenAlex.
- Guillain-Barre syndrome in patients receiving chimeric antigen receptor T-cell therapy: an individual participant data meta-analysis.Frontiers in neurology · 2025Pooled it
- Gender disparities in cognitive impairment across neurological autoimmune disorders: a systematic review.Frontiers in neurology · 2025Pooled it
- Patients' experiences and perceptions of Guillain-Barré syndrome: A systematic review and meta-synthesis of qualitative research.PloS one · 2021Pooled it
- Neuropsychiatric manifestations in inflammatory neuropathies: A systematic review.Muscle & nerve · 2016Pooled it
- Multidisciplinary care for Guillain-Barré syndrome.The Cochrane database of systematic reviews · 2010Pooled it
- Observer blind randomised controlled trial of a tailored home exercise programme versus usual care in people with stable inflammatory immune mediated neuropathy.BMC neurology · 2015Trial
- Article
- Guillain-Barré Syndrome Emerging From Syringomyelia Management: A Case Report.Case reports in medicine · 2026Article
- Evolving understanding of Guillain-Barré syndrome pathophysiology and the central role of the classical complement pathway in axonal injury.Frontiers in neurology · 2025Article
- Guillain-Barré syndrome.Nature reviews. Disease primers · 2024Article
- Unique Clinical and Psychiatric Challenges in Elderly Patients With Guillain-Barré Syndrome: A Case Series.Cureus · 2024Article
- Long-term outcomes of patients affected by Guillain-Barré syndrome in Colombia after the Zika virus epidemic.Journal of the neurological sciences · 2024Article
- Incidence of Guillain-Barré syndrome in the world between 1985 and 2020: A systematic review.Global epidemiology · 2023Review
- Prognosis of Guillain-Barré Syndrome Linked to COVID-19 Vaccination.Brain sciences · 2022Article
- Guillain-Barré syndrome in low-income and middle-income countries: challenges and prospects.Nature reviews. Neurology · 2021Review
- Intensive Care and Treatment of Severe Guillain-Barré Syndrome.Frontiers in pharmacology · 2021Review
- Exploring the experiences of having Guillain-Barré Syndrome: A qualitative interview study.Health expectations : an international journal of public participation in health care and health policy · 2020Article
- Psychiatric Sequelae of Guillain-Barré Syndrome: Towards a Multidisciplinary Team Approach.Cureus · 2020Review
- Depressive Syndromes in Autoimmune Disorders of the Nervous System: Prevalence, Etiology, and Influence.Frontiers in psychiatry · 2018Review
- Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledTo examine factors impacting long-term health-related outcomes in survivors of Guillain-Barre syndrome (GBS). Seventy-six consecutive patients with definite GBS admitted to the Royal Melbourne Hospital (1996-2009) were reviewed in the neurorehabilitation clinics. They underwent a structured interview designed to assess the impact of GBS on their current activity and restriction in participation using validated questionnaires: Functional Independence Measure (FIM), Perceived Impact of Problem Profile (PIPP) and Depression Anxiety Stress Scale (DASS). Their sociodemographic and disease severity data were obtained from the medical record. The 76 patients [60% male, mean age 56 years, median time since GBS 6 years (range 1-14 years)] showed good functional recovery (median motor FIM score 90). However, 16% reported moderate to extreme impact on their ability to participate in work, family, and social activities; and 22% substantial impact on mood, confidence and ability to live independently. More reported moderate to extreme depression (18%), anxiety (22%) and stress (17%) compared with the normative Australian population (13%). Factors associated with poorer current level of functioning and wellbeing included: females, older patients (57+ years), acute hospital stay (>11 days), those treated in intensive care and those discharged to rehabilitation. No associations were found between the Medical Research Council (MRC) Motor Scale Rating scores at admission, nor time since GBS diagnosis (≤6 vs. >6 years) on outcomes used.
conclusionGBS is complex and requires long-term management of psychological sequelae impacting activity and participation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.