Evidence map›Paper›PMID 20625449›Full record

ArticleExpert review of ophthalmology2010

Fuchs' corneal dystrophy.

Allen O Eghrari, John D Gottsch

Open access · greenAbstract read
In one paragraph

Article in Expert review of ophthalmology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
3.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 126 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Screening with the Bilateral Corneal Symmetry 3-D Analyzer.International journal of environmental research and public health · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Diseases of the corneal endothelium.Experimental eye research · 2021
    Review
  13. Peripheral-to-central ratio of Guttae: validity and reliability of an objective method to characterize severity of Fuchs endothelial corneal dystrophy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
    Article
  14. Review
  15. Article
  16. Review
  17. Collagen Remodeling Plays a Pivotal Role in Endothelial Corneal Dystrophies.Investigative ophthalmology & visual science · 2020
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Allen O EghrariCataract, Cornea and External Disease Service, Wilmer Eye Institute, 600 North Wolfe Street, 317 Maumenee Building, Baltimore, MD 21287, USA.
John D Gottsch
National Eye Institute · US

Funding

Genetics of Fuchs Corneal DystrophyR01EY016835 · NEI · JOHNS HOPKINS UNIVERSITY · PI GOTTSCH, JOHN D · 2007 to 2017
$5.7M
NEI NIH HHS R01 EY016835
6 · The paper itself

Abstract

Fuchs' corneal dystrophy (FCD) is a progressive, hereditary disease of the cornea first described a century ago by the Austrian ophthalmologist Ernst Fuchs. Patients often present in the fifth to sixth decade of life with blurry morning vision that increases in duration as the disease progresses. Primarily a condition of the posterior cornea, characteristic features include the formation of focal excrescences of Descemet membrane termed 'guttae', loss of endothelial cell density and end-stage disease manifested by corneal edema and the formation of epithelial bullae. Recent advances in our understanding of the genetic and pathophysiological mechanisms of the disease, as well as the application of new imaging modalities and less invasive surgical procedures, present new opportunities for improved outcomes among patients with FCD.

Identifiers

PMID20625449
PMCPMC2897712
OpenAlexW1973455981

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.