Trial reportJournal of biomedicine & biotechnology2010
Effects of sizes and conformations of fish-scale collagen peptides on facial skin qualities and transdermal penetration efficiency.
Trial report in Journal of biomedicine & biotechnology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.
- Effects of Hydrolyzed Collagen as a Dietary Supplement on Fibroblast Activation: A Systematic Review.Nutrients · 2024Pooled it
- Deep eutectic solvent-mediated extraction of collagen peptides from sturgeon skin: Molecular-weight control and mechanistic insights.Food chemistry: X · 2026Article
- Article
- Fish By-Products Utilization in Food and Health: Extraction Technologies, Bioactive, and Sustainability Challenges.Food science & nutrition · 2025Review
- Potential of cannabidiol as acne and acne scar treatment: novel insights into molecular pathways of pathophysiological factors.Archives of dermatological research · 2024Article
- Attenuative effects of collagen peptide from milkfish (Food science & nutrition · 2024Article
- Challenges and strategies for collagen delivery for tissue regeneration.Journal of public health in Africa · 2023Article
- A Comprehensive Review on Collagen Type I Development of Biomaterials for Tissue Engineering: From Biosynthesis to Bioscaffold.Biomedicines · 2022Review
- Theophylline-encapsulated Nile Tilapia fish scale-based collagen nanoparticles effectively target the lungs of male Sprague-Dawley rats.Scientific reports · 2022Article
- Article
- Effect of Fish Bone Bioactive Peptides on Oxidative, Inflammatory and Pigmentation Processes Triggered by UVB Irradiation in Skin Cells.Molecules (Basel, Switzerland) · 2021Article
- Porcine placenta hydrolysate as an alternate functional food ingredient: In vitro antioxidant and antibacterial assessments.PloS one · 2021Article
- Characterization and biological evaluation of a novel silver nanoparticle-loaded collagen-chitosan dressing.Regenerative biomaterials · 2020Article
- Natural hydrogels R&D process: technical and regulatory aspects for industrial implementation.Journal of materials science. Materials in medicine · 2020Review
- New Nanofibers Based on Protein By-Products with Bioactive Potential for Tissue Engineering.Materials (Basel, Switzerland) · 2020Article
- Collagen Hydrolysates for Skin Protection: Oral Administration and Topical Formulation.Antioxidants (Basel, Switzerland) · 2020Review
- Reclamation of Fishery Processing Waste: A Mini-Review.Molecules (Basel, Switzerland) · 2019Article
- Marine Collagen: An Emerging Player in Biomedical applications.Journal of food science and technology · 2015Review
- Effects of Concentration and Reaction Time of Trypsin, Pepsin, and Chymotrypsin on the Hydrolysis Efficiency of Porcine Placenta.Korean journal for food science of animal resources · 2014Article
- Human skin permeation of emerging mycotoxins (beauvericin and enniatins).Journal of exposure science & environmental epidemiologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fish-scale collagen peptides (FSCPs) were prepared using a given combination of proteases to hydrolyze tilapia (Oreochromis sp.) scales. FSCPs were determined to stimulate fibroblast cells proliferation and procollagen synthesis in a time- and dose-dependent manner. The transdermal penetration capabilities of the fractionationed FSCPs were evaluated using the Franz-type diffusion cell model. The heavier FSCPs, 3500 and 4500 Da, showed higher cumulative penetration capability as opposed to the lighter FSCPs, 2000 and 1300 Da. In addition, the heavier seemed to preserve favorable coiled structures comparing to the lighter that presents mainly as linear under confocal scanning laser microscopy. FSCPs, particularly the heavier, were concluded to efficiently penetrate stratum corneum to epidermis and dermis, activate fibroblasts, and accelerate collagen synthesis. The heavier outweighs the lighter in transdermal penetration likely as a result of preserving the given desired structure feature.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.