Evidence map›Paper›PMID 20624718›Full record

ArticleDatabase : the journal of biological databases and curation2010

PROFESS: a PROtein function, evolution, structure and sequence database.

Thomas Triplet, Matthew D Shortridge, Mark A Griep, Jaime L Stark, Robert Powers, Peter Revesz

Abstract read
In one paragraph

Article in Database : the journal of biological databases and curation, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Bacterial protein structures reveal phylum dependent divergence.Computational biology and chemistry · 2011
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Thomas TripletDepartment of Computer Science and Engineering, University of Nebraska-Lincoln, Lincoln, NE 68588-0115, USA.
Matthew D Shortridge
Mark A Griep
Jaime L Stark
Robert Powers
Peter Revesz

Funding

EXTRAMURAL RESEARCH FACILITIES CONSTRUCTIONC06RR015468 · NCRR · UNIVERSITY OF NEBRASKA LINCOLN · PI PAUL, PREM S · 2000 to 2000
$2.0M
Revealing Functions for Newly Discovered Proteins by FAST-NMRR21AI081154 · NIAID · UNIVERSITY OF NEBRASKA LINCOLN · PI POWERS, ROBERT · 2009 to 2010
$376k
NCRR NIH HHS C06 RR015468NCRR NIH HHS RR015468-01NIAID NIH HHS R21AI081154
6 · The paper itself

Abstract

The proliferation of biological databases and the easy access enabled by the Internet is having a beneficial impact on biological sciences and transforming the way research is conducted. There are approximately 1100 molecular biology databases dispersed throughout the Internet. To assist in the functional, structural and evolutionary analysis of the abundant number of novel proteins continually identified from whole-genome sequencing, we introduce the PROFESS (PROtein Function, Evolution, Structure and Sequence) database. Our database is designed to be versatile and expandable and will not confine analysis to a pre-existing set of data relationships. A fundamental component of this approach is the development of an intuitive query system that incorporates a variety of similarity functions capable of generating data relationships not conceived during the creation of the database. The utility of PROFESS is demonstrated by the analysis of the structural drift of homologous proteins and the identification of potential pancreatic cancer therapeutic targets based on the observation of protein-protein interaction networks. Database URL: http://cse.unl.edu/~profess/

Indexed as

Databases, ProteinAmino Acid SequenceData MiningEvolution, MolecularHumansInternetPancreatic NeoplasmsProtein Interaction MappingProteinsSequence AlignmentStructural Homology, ProteinProteins

Identifiers

PMID20624718
PMCPMC2911846

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.