Trial reportBMC surgery2010
Decompressive laparotomy with temporary abdominal closure versus percutaneous puncture with placement of abdominal catheter in patients with abdominal compartment syndrome during acute pancreatitis: background and design of multicenter, randomised, controlled study.
Trial report in BMC surgery, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Interventions for necrotising pancreatitis.The Cochrane database of systematic reviews · 2016Pooled it
- Acute Pancreatitis Presenting With ST-Segment Elevation and Marked Troponin Elevation: A Diagnostic Dilemma in a Resource-Limited Setting-A Case Report.Clinical case reports · 2026Article
- Successful treatment with decompressive laparotomy for abdominal compartment syndrome induced by asparaginase-associated pancreatitis in a pediatric patient with acute lymphoblastic leukemia: a case report.Translational pediatrics · 2025Article
- Managing complicated pancreatitis with more knowledge and a bigger toolbox!Trauma surgery & acute care open · 2025Review
- Surgical decompression for the management of abdominal compartment syndrome with severe acute pancreatitis: A narrative review.World journal of gastrointestinal surgery · 2023Review
- Abdominal Compartment Syndrome-When Is Surgical Decompression Needed?Diagnostics (Basel, Switzerland) · 2021Review
- Evaluation and management of acute pancreatitis.World journal of clinical cases · 2019Review
- Tension pneumoperitoneum: Case report of a rare form of acute abdominal compartment syndrome.International journal of surgery case reports · 2019Article
- 2019 WSES guidelines for the management of severe acute pancreatitis.World journal of emergency surgery : WJES · 2019Review
- Interventional Treatment of Abdominal Compartment Syndrome during Severe Acute Pancreatitis: Current Status and Historical Perspective.Gastroenterology research and practice · 2016Review
- Surgery for Acute Pancreatitis.The Indian journal of surgery · 2015Article
- Study on acute recent stage pancreatitis.World journal of gastroenterology · 2014Review
- Abdominal compartment syndrome in severe acute pancreatitis treated with percutaneous catheter drainage.Clinical endoscopy · 2014Article
- Effect of obesity and decompressive laparotomy on mortality in acute pancreatitis requiring intensive care unit admission.World journal of surgery · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDevelopment of abdominal compartment syndrome (ACS) in patients with severe acute pancreatitis (SAP) has a strong impact on the course of disease. Number of patients with this complication increases during the years due more aggressive fluid resuscitation, much bigger proportion of patients who is treated conservatively or by minimal invasive approach, and efforts to delay open surgery. There have not been standard recommendations for a surgical or some other interventional treatment of patients who develop ACS during the SAP. The aim of DECOMPRESS study was to compare decompresive laparotomy with temporary abdominal closure and percutaneus puncture with placement of abdominal catheter in these patients.
methodsOne hundred patients with ACS will be randomly allocated to two groups: I) decompresive laparotomy with temporary abdominal closure or II) percutaneus puncture with placement of abdominal catheter. Patients will be recruited from five hospitals in Belgrade during two years period. The primary endpoint is the mortality rate within hospitalization. Secondary endpoints are time interval between intervention and resolving of organ failure and multi organ dysfunction syndrome, incidence of infectious complications and duration of hospital and ICU stay. A total sample size of 100 patients was calculated to demonstrate that decompresive laparotomy with temporary abdominal closure can reduce mortality rate from 60% to 40% with 80% power at 5% alfa.
conclusionDECOMPRESS study is designed to reveal a reduction in mortality and major morbidity by using decompresive laparotomy with temporary abdominal closure in comparison with percutaneus puncture with placement of abdominal catheter in patients with ACS during SAP.
trial registrationClinicalTrials.gov Identifier: NTC00793715.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.