ArticleFamilial cancer2010
Pancreatic cancer risk counselling and screening: impact on perceived risk and psychological functioning.
Article in Familial cancer, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04024345 (Surveillance Program in High-risk Individuals for Pancreatic Cancer), which is not on this map. Cited by 34 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Surveillance Program in High-risk Individuals for Pancreatic Cancer: Prospective Analysis of the Emotional Impact
Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Pooled it
- Screening for pancreatic cancer in familial high-risk individuals: A systematic review.World journal of gastroenterology · 2015Pooled it
- Psychosocial morbidity in TP53 mutation carriers: is whole-body cancer screening beneficial?Familial cancer · 2017Trial
- Five-year psychological impact and surveillance compliance in the Australian Pancreatic Cancer Screening Program.Familial cancer · 2026Article
- Hidden SVA retrotransposon insertion in BRCA1 revealed by nanopore targeted sequencing causes hereditary breast and ovarian cancer.Journal of human genetics · 2025Article
- Article
- Psychological Distress and Quality of Life in Families With a Germline CDKN2A Pathogenic Variant.Molecular genetics & genomic medicine · 2025Article
- The role of endoscopic ultrasound in the detection of pancreatic lesions in high-risk individuals.Familial cancer · 2024Review
- Assessment of the Psychosocial Impact of Pancreatic Cancer Surveillance in High-Risk Individuals.Cancers · 2023Article
- Familial pancreatic cancer: a case study and review of the psychosocial effects of diagnoses on families.Hereditary cancer in clinical practice · 2023Article
- Clinical risk management of breast, ovarian, pancreatic, and prostatic cancers for BRCA1/2 variant carriers in Japan.Journal of human genetics · 2023Review
- Health-related quality of life and anxiety levels among patients under surveillance for intraductal papillary mucinous neoplasm.BMC gastroenterology · 2023Observational
- Review
- Familial Pancreatic Cancer.Gastroenterology clinics of North America · 2022Review
- Pancreatic cancer risk to siblings of probands in bilineal cancer settings.Genetics in medicine : official journal of the American College of Medical Genetics · 2022Article
- Clinical Data Prediction Model to Identify Patients With Early-Stage Pancreatic Cancer.JCO clinical cancer informatics · 2021Article
- Patient-reported burden of intensified surveillance and surgery in high-risk individuals under pancreatic cancer surveillance.Familial cancer · 2020Article
- Long-term positive psychological outcomes in an Australian pancreatic cancer screening program.Familial cancer · 2020Article
- Genetic counselling and personalised risk assessment in the Australian pancreatic cancer screening program.Hereditary cancer in clinical practice · 2019Article
- CDKN2A/CDK4 Status in Greek Patients with Familial Melanoma and Association with Clinico-epidemiological Parameters.Acta dermato-venereologica · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Individuals at increased risk for pancreatic cancer who undergo screening can experience psychological and emotional distress. The objective of this study is to determine whether individuals participating in a pancreatic cancer screening program experience disruptions in risk perception, cancer-related anxiety or emotional distress. A pretestposttest design was used to examine perceived risk and psychological functioning of individuals participating in a pancreatic cancer screening protocol. The screening protocol includes genetic counselling, transcutaneous abdominal ultrasound, magnetic resonance imaging, and blood collection and eligible participants included individuals with a family history of pancreatic cancer or BRCA2 mutation carriers. At baseline, participants (n = 198) showed low to moderate levels of risk perception, pancreatic cancer-related anxiety, and general distress. Participants with familial pancreatic cancer (FPC) (n = 131) endorsed higher risk perception of pancreatic cancer than the BRCA2 carriers (n = 67) (perceived lifetime risk 42 vs. 15%), but did not differ on cancer worry or general distress prior to the first study appointment. From baseline to 3 months follow-up, no significant time or time by group interactions emerged on risk perception or general distress, but cancer worry decreased over time for the FPC group regardless of the number of affected relatives. Our findings indicate that participation in a pancreatic cancer screening program does not lead to a significant increase in risk perception, cancer worry, or general distress and that participants with high baseline levels of risk perception and distress may benefit from a more comprehensive risk assessment and psychological support.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.