Evidence map›Paper›PMID 20622976›Full record

ArticleThe open allergy journal2009

Phthalates, Pesticides, and Bisphenol-A Exposure and the Development of Nonoccupational Asthma and Allergies: How Valid Are the Links?

Eun Soo Kwak, Allan Just, Robin Whyatt, Rachel L Miller

Open access · diamondAbstract read
In one paragraph

Article in The open allergy journal, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. The interplay between environmental exposures and COVID-19 risks in the health of children.Environmental health : a global access science source · 2021
    Article
  3. Article
  4. COVID-19, an opportunity to reevaluate the correlation between long-term effects of anthropogenic pollutants on viral epidemic/pandemic events and prevalence.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2020
    Review
  5. Bisphenol a Exposure, DNA Methylation, and Asthma in Children.International journal of environmental research and public health · 2020
    Article
  6. Article
  7. Article
  8. Article
  9. Environmental health perspectives · 2017
    Article
  10. Article
  11. Article
  12. Occupational risks and pregnancy and infant health outcomes in Florida farmworkers.International journal of environmental research and public health · 2014
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Exposure to triclosan augments the allergic response to ovalbumin in a mouse model of asthma.Toxicological sciences : an official journal of the Society of Toxicology · 2013
    Article
  18. The effects of maternal exposure to bisphenol A on allergic lung inflammation into adulthood.Toxicological sciences : an official journal of the Society of Toxicology · 2012
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Eun Soo KwakDivision of Pulmonary, Allergy, and Critical Care Medicine, Columbia University College of Physicians and Surgeons, USA.
Allan Just
Robin Whyatt
Rachel L Miller
Columbia University · US

Funding

Windows of Susceptibility to PAH/DEP Exposure and AsthmaP50ES015905 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PERERA, FREDERICA P · 2007 to 2011
$10.3M
Phthalate Exposure and Inner City Pediatric AsthmaR01ES014393 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WHYATT, ROBIN MARJORIE · 2007 to 2011
$3.1M
NIEHS NIH HHS P50 ES015905NIEHS NIH HHS R01 ES014393
6 · The paper itself

Abstract

Phthalates, pesticides, and bisphenol-A (BPA) are three groups of chemicals, implicated in endocrine disruption and commonly found in the local environment, that have been implicated in the pathogenesis of asthma and allergies [1-3]. Multiple observational studies have demonstrated an association between exposure to phthalates and the development of asthma and allergies in humans. Associations with exposure to pesticides and BPA and the development of respiratory disease are less clear. However, recent evidence suggests that prenatal or early postnatal exposure to BPA may be deleterious to the developing immune system. Future cohort-driven epidemiological or translational research should focus on determining whether these ubiquitous chemicals contribute to the development of asthma and allergies in humans, and attempt to establish the routes and mechanisms by which they operate. Determining dose-response relationships will be important to establishing safe levels of these chemicals in the environment and in consumer products. Attempts to reduce exposures to chemicals such as phthalates, pesticides, and BPA may have environmental repercussions as well as public health impact for the developing child.

Identifiers

PMID20622976
PMCPMC2901120
OpenAlexW2151444856

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.