Evidence map›Paper›PMID 20622885›Full record

ArticleNature biotechnology2010

Genome sequence of the model mushroom Schizophyllum commune.

Robin A Ohm, Jan F de Jong, Luis G Lugones, Andrea Aerts, Erika Kothe, Jason E Stajich, Ronald P de Vries, Eric Record, Anthony Levasseur, Scott E Baker and 22 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature biotechnology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 247 papers.

0numbers the graph read from it
0cells of the map it votes in
247citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

247 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Solid-state NMR spectroscopy reveals unique properties ofCell surface (Amsterdam, Netherlands) · 2025
    Article
  11. Article
  12. Dissecting the homeodomainbioRxiv : the preprint server for biology · 2025
    Article
  13. Review
  14. Article
  15. Increased Cellulase Activity of Schizophyllum commune EO22 in Binary Associations with Streptomycetes.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2025
    Article
  16. Article
  17. Article
  18. Recurrent Pulmonary Infection Caused byRespirology case reports · 2025
    Article
  19. Characterization of Homeodomain Proteins at the Aβ Sublocus inJournal of fungi (Basel, Switzerland) · 2025
    Article
  20. Article

187 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Robin A OhmDepartment of Microbiology and Kluyver Centre for Genomics of Industrial Fermentation, Utrecht University, Utrecht, The Netherlands.
Jan F de Jong
Luis G Lugones
Andrea Aerts
Erika Kothe
Jason E Stajich
Ronald P de Vries
Eric Record
Anthony Levasseur
Scott E Baker
Kirk A Bartholomew
Pedro M Coutinho
Susann Erdmann
Thomas J Fowler
Allen C Gathman
Vincent Lombard
Bernard Henrissat
Nicole Knabe
Ursula Kües
Walt W Lilly
Erika Lindquist
Susan Lucas
Jon K Magnuson
François Piumi
Marjatta Raudaskoski
Asaf Salamov
Jeremy Schmutz
Francis W M R Schwarze
Patricia A vanKuyk
J Stephen Horton
Igor V Grigoriev
Han A B Wösten

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Much remains to be learned about the biology of mushroom-forming fungi, which are an important source of food, secondary metabolites and industrial enzymes. The wood-degrading fungus Schizophyllum commune is both a genetically tractable model for studying mushroom development and a likely source of enzymes capable of efficient degradation of lignocellulosic biomass. Comparative analyses of its 38.5-megabase genome, which encodes 13,210 predicted genes, reveal the species's unique wood-degrading machinery. One-third of the 471 genes predicted to encode transcription factors are differentially expressed during sexual development of S. commune. Whereas inactivation of one of these, fst4, prevented mushroom formation, inactivation of another, fst3, resulted in more, albeit smaller, mushrooms than in the wild-type fungus. Antisense transcripts may also have a role in the formation of fruiting bodies. Better insight into the mechanisms underlying mushroom formation should affect commercial production of mushrooms and their industrial use for producing enzymes and pharmaceuticals.

Indexed as

Base SequenceModels, BiologicalFruiting Bodies, FungalFungal ProteinsGene Expression ProfilingGene Expression Regulation, DevelopmentalGene Expression Regulation, PlantGenes, Mating Type, FungalGenetic LociGenome, FungalSchizophyllumTranscription FactorsWoodFungal ProteinsTranscription Factors

Identifiers

PMID20622885

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.