ReviewAmerican journal of physiology. Heart and circulatory physiology2010
The mitochondrial component of intracrine action.
Review in American journal of physiology. Heart and circulatory physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed.
- Receptor-mediated endocytosis by Megalin: Exploring its role in ligand interaction and disease mechanisms.Genes & diseases · 2026Review
- Deletion of Megalin in Kidney Tubular Epithelium Up-Regulates TGFβ1 Signaling, Aggravates Ischemia/Reperfusion Kidney Injury, and Accelerates the Progression to Chronic Kidney Disease.The American journal of pathology · 2026Article
- New Insights in the Diagnostic Potential of Sex Hormone-Binding Globulin (SHBG)-Clinical Approach.Biomedicines · 2025Review
- Interactions between leucines within the signal peptides of megalin and stanniocalcin-1 are crucial for regulation of mitochondrial metabolism.Laboratory investigation; a journal of technical methods and pathology · 2022Article
- Megalin-Mediated Trafficking of Mitochondrial Intracrines: Relevance to Signaling and Metabolism.Journal of cellular immunology · 2021Article
- Classic and Novel Sex Hormone Binding Globulin Effects on the Cardiovascular System in Men.International journal of endocrinology · 2021Review
- Intratubular, Intracellular, and Mitochondrial Angiotensin II/ATFrontiers in physiology · 2021Review
- Evidence for a Physiological Mitochondrial Angiotensin II System in the Kidney Proximal Tubules: Novel Roles of Mitochondrial Ang II/ATHypertension (Dallas, Tex. : 1979) · 2020Article
- Stanniocalcin-1 Alleviates Contrast-Induced Acute Kidney Injury by Regulating Mitochondrial Quality Control via the Nrf2 Pathway.Oxidative medicine and cellular longevity · 2020Article
- Megalin mediates plasma membrane to mitochondria cross-talk and regulates mitochondrial metabolism.Cellular and molecular life sciences : CMLS · 2018Article
- Article
- Angiotensinogen import in isolated proximal tubules: evidence for mitochondrial trafficking and uptake.American journal of physiology. Renal physiology · 2017Article
- Stanniocalcin-1 attenuates ischemic cardiac injury and response of differentiating monocytes/macrophages to inflammatory stimuli.Translational research : the journal of laboratory and clinical medicine · 2016Article
- Evidence for a mitochondrial angiotensin-(1-7) system in the kidney.American journal of physiology. Renal physiology · 2016Article
- The Cooperative Effect of Local Angiotensin-II in Liver with Adriamycin Hepatotoxicity on Mitochondria.Medical science monitor : international medical journal of experimental and clinical research · 2016Article
- Mitochondrial uncoupling proteins regulate angiotensin-converting enzyme expression: crosstalk between cellular and endocrine metabolic regulators suggested by RNA interference and genetic studies.Inside the cell · 2016Article
- Age-Related Macular Degeneration and Intracrine Biology: An Hypothesis.Ochsner journal · 2016Review
- Stanniocalcin-1 inhibits thrombin-induced signaling and protects from bleomycin-induced lung injury.Scientific reports · 2015Article
- Stanniocalcin-1 inhibits renal ischemia/reperfusion injury via an AMP-activated protein kinase-dependent pathway.Journal of the American Society of Nephrology : JASN · 2015Article
- Severe Nephrotoxic Nephritis following Conditional and Kidney-Specific Knockdown of Stanniocalcin-1.PloS one · 2015Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
In recent years the actions of intracellular-acting, extracellular signaling proteins/peptides (intracrines) have become increasingly defined. General principles of intracrine action have been proposed. Mitochondria represent one locus of intracrine action, and thus far, angiotensin II, transforming growth factor-beta, growth hormone, atrial natriuretic peptide, Wnt 13, stanniocalcin, other renin-angiotensin system components, and vascular endothelial-derived growth factor, among others, have been shown to be mitochondria-localizing intracrines. The implications of this mitochondrial intracrine biology are discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.