ArticleJournal of bacteriology2010
Transcriptional regulation of the heterocyst patterning gene patA from Anabaena sp. strain PCC 7120.
Article in Journal of bacteriology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 33 citations in OpenAlex.
- Distinct cell division features inJournal of bacteriology · 2025Review
- A cyanobacterial chemotaxis-like system controls phototactic orientation via phosphorylation of two antagonistic response regulators.microLife · 2024Article
- A proteolytic pathway coordinates cell division and heterocyst differentiation in the cyanobacteriumProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Terminal heterocyst differentiation in the Anabaena patA mutant as a result of post-transcriptional modifications and molecular leakage.PLoS computational biology · 2022Article
- Mathematical models of nitrogen-fixing cell patterns in filamentous cyanobacteria.Frontiers in cell and developmental biology · 2022Review
- Article
- Functional Dissection of Genes Encoding DNA Polymerases Based on Conditional Mutants in the Heterocyst-Forming CyanobacteriumFrontiers in microbiology · 2020Article
- Article
- Formation and maintenance of nitrogen-fixing cell patterns in filamentous cyanobacteria.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Deep sequencing of HetR-bound DNA reveals novel HetR targets in Anabaena sp. strain PCC7120.BMC microbiology · 2014Article
- Biased inheritance of the protein PatN frees vegetative cells to initiate patterned heterocyst differentiation.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Identification of the HetR recognition sequence upstream of hetZ in Anabaena sp. strain PCC 7120.Journal of bacteriology · 2012Article
- Mutations in genes patA and patL of Anabaena sp. strain PCC 7120 result in similar phenotypes, and the proteins encoded by those genes may interact.Journal of bacteriology · 2011Article
- Genome fluctuations in cyanobacteria reflect evolutionary, developmental and adaptive traits.BMC evolutionary biology · 2011Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The filamentous cyanobacterium Anabaena sp. strain PCC 7120 forms a periodic pattern of nitrogen-fixing heterocysts when grown in the absence of combined nitrogen. PatA is necessary for proper patterning of heterocysts along filaments. In this study, apparent transcriptional start points (tsps) were identified at nucleotides -305, -614, and -645 relative to the translational start site (-305, -614, and -645 tsps). Transcriptional reporter fusions were used to show that transcription from the -305 tsp was induced in all cells of filaments in response to nitrogen deprivation, required hetR for induction, and increased in a patA mutant. Transcription from -614/-645 tsp reporter fusions was spatially regulated and occurred primarily in cells that would become heterocysts. Complementation of a patA mutant strain by alleles encoding substitutions in, or deletion of, the putative phosphoacceptor C-terminal domain indicates that the PATAN domain can function independently of the C-terminal domain of PatA. Localization of a ring of PatA-GFP at sites of cell division, as well as the formation of enlarged cells with altered cell morphology when patA was overexpressed, suggests that PatA may participate in cell division.
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