ArticleBehavioural brain research2011
Deficient proactive interference of eyeblink conditioning in Wistar-Kyoto rats.
Article in Behavioural brain research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 21 citations in OpenAlex.
- Cardiorespiratory Response to Moderate Hypercapnia in Female College Students Expressing Behaviorally Inhibited Temperament.Frontiers in neuroscience · 2020Article
- Inhibited Personality Temperaments Translated Through Enhanced Avoidance and Associative Learning Increase Vulnerability for PTSD.Frontiers in psychology · 2019Review
- Adolescent D-amphetamine treatment in a rodent model of ADHD: Pro-cognitive effects in adolescence without an impact on cocaine cue reactivity in adulthood.Behavioural brain research · 2016Article
- Enhanced Eyeblink Conditioning in Behaviorally Inhibited Individuals is Disrupted by Proactive Interference Following US Alone Pre-exposures.Frontiers in behavioral neuroscience · 2016Article
- Editorial: Avoidance: From Basic Science to Psychopathology.Frontiers in behavioral neuroscience · 2016Article
- Avoidance expression in rats as a function of signal-shock interval: strain and sex differences.Frontiers in behavioral neuroscience · 2015Article
- Attenuated inhibition of medium spiny neurons participates in the pathogenesis of childhood depression.Neural regeneration research · 2014Article
- ITI-Signals and Prelimbic Cortex Facilitate Avoidance Acquisition and Reduce Avoidance Latencies, Respectively, in Male WKY Rats.Frontiers in behavioral neuroscience · 2014Article
- Enhanced discriminative fear learning of phobia-irrelevant stimuli in spider-fearful individuals.Frontiers in behavioral neuroscience · 2014Article
- Avoidance as expectancy in rats: sex and strain differences in acquisition.Frontiers in behavioral neuroscience · 2014Article
- Enhanced conditioned eyeblink response acquisition and proactive interference in anxiety vulnerable individuals.Frontiers in behavioral neuroscience · 2012Article
- Behaviorally inhibited temperament is associated with severity of post-traumatic stress disorder symptoms and faster eyeblink conditioning in veterans.Stress (Amsterdam, Netherlands) · 2012Article
- Classical and instrumental conditioning of eyeblink responses in Wistar-Kyoto and Sprague-Dawley rats.Behavioural brain research · 2011Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Wistar-Kyoto (WKY) rats exhibit behavioral inhibition and model anxiety vulnerability. Although WKY rats exhibit faster active avoidance acquisition, simple associative learning or the influence of proactive interference (PI) has not been adequately assessed in this strain. Therefore, we assessed eyeblink conditioning and PI in WKY and outbred Sprague-Dawley (SD) rats. Rats were pre-exposed to either the experimental context, the conditioned stimulus (CS), the unconditional stimulus (US), or the CS & US in an explicitly unpaired (EUP) manner, to examine latent inhibition (LI), US pre-exposure effect, or learned irrelevance (LIRR), respectively. Immediately following pre-exposures, rats were trained in a delay-type paradigm (500 ms CS coterminating with a 10-ms US) for one session. During training SD rats exhibited LI and inhibition from US pre-exposures without evidence of LIRR. PI was less evident in WKY rats; LI was absent in WKY rats. Even in the context of reduced PI to CS-alone and US-alone pre-exposures, LIRR was not apparent in WKY rats. The more normal acquisition rates exhibited by WKY rats, under conditions which degrade performance in SD rats, increases the overall likelihood for WKY rats to acquire defensive responses. Enhanced acquisition of defensive responses is a means by which anxiety vulnerability (e.g., behavioral inhibition) is translated to anxiety psychopathology.
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