Evidence map›Paper›PMID 20621127›Full record

ArticleBehavioural brain research2010

The modulatory effects of rostral ventromedial medulla on air-puff evoked microarousals in rats.

H Foo, Katherine Crabtree, Peggy Mason

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Behavioural brain research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Diencephalic and brainstem mechanisms in migraine.Nature reviews. Neuroscience · 2011
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

H FooDepartment of Neurobiology, University of Chicago, 947 East 58th Street, Chicago, IL 60637, United States. hfoo@bsd.uchicago.edu
Katherine Crabtree
Peggy Mason

Funding

Physiology of Raphe Magnus Cells During Wake and SleepR01DA022978 · NIDA · UNIVERSITY OF CHICAGO · PI MASON, PEGGY · 2007 to 2011
$1.8M
PHYSIOLOGY OF RAPHE MAGNUS CELLS DURING WAKE AND SLEEPR01MH060291 · NIMH · UNIVERSITY OF CHICAGO · PI MASON, PEGGY · 1999 to 2003
$770k
NIDA NIH HHS R01 DA022978NIMH NIH HHS R01 MH060291
6 · The paper itself

Abstract

This study tested whether the duration of microarousals from sleep evoked by innocuous air-puff is affected by intra-RVM administration of neurotensin and bicuculline, pharmacological manipulations that affect on and off cell activity. Air-puff evoked microarousal duration was unaffected by 0.05ng neurotensin, but decreased by 502ng neurotensin, and 5 and 50ng bicuculline. These results suggest a putative role for off cells in protecting sleep from interruption by non-noxious stimuli.

Indexed as

SleepAnimalsArousalBicucullineElectroencephalographyElectromyographyGABA-A Receptor AntagonistsMaleMedulla OblongataNeuronsNeurotensinPhysical StimulationRatsRats, Sprague-DawleyBicucullineGABA-A Receptor AntagonistsNeurotensin

Identifiers

PMID20621127
PMCPMC2931329

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.