Evidence map›Paper›PMID 20621045›Full record

ArticleCell stem cell2010

Reprogramming of human peripheral blood cells to induced pluripotent stem cells.

Judith Staerk, Meelad M Dawlaty, Qing Gao, Dorothea Maetzel, Jacob Hanna, Cesar A Sommer, Gustavo Mostoslavsky, Rudolf Jaenisch

Abstract read
In one paragraph

Article in Cell stem cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 228 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
228citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

228 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Computational Network Analysis for Defining Transcriptional Programs.Methods in molecular biology (Clifton, N.J.) · 2027
    Article
  5. Article
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  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Current Development of iPSC-Based Modeling in Neurodegenerative Diseases.International journal of molecular sciences · 2025
    Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article

168 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Judith StaerkThe Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA.
Meelad M Dawlaty
Qing Gao
Dorothea Maetzel
Jacob Hanna
Cesar A Sommer
Gustavo Mostoslavsky
Rudolf Jaenisch

Funding

HARVARD CLINICAL AND TRANSLATIONAL SCIENCE CENTER (UL1)UL1RR025758 · NCRR · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2008 to 2011
$91.4M
GENOMIC IMPRINTING AND THE CLONING OF MICER37CA084198 · NCI · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI JAENISCH, RUDOLF · 2000 to 2008
$9.2M
Epigenetics, Stem Cells, and CancerR01CA087869 · NCI · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI JAENISCH, RUDOLF · 2001 to 2010
$8.2M
In Vitro Reprogramming of Somatic Cells into Pluripotent ES-like CellsR37HD045022 · NICHD · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI JAENISCH, RUDOLF · 2009 to 2017
$7.5M
Nuclear Cloning and the Reprogramming of the GenomeR01HD045022 · NICHD · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI JAENISCH, RUDOLF · 2003 to 2008
$4.7M
Programming and Reprogramming Human CellsR01CA084198 · NCI · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI JAENISCH, RUDOLF · 2009 to 2013
$4.3M
NCI NIH HHS 5-R37-CA084198NCI NIH HHS 5-RO1-CA087869NCI NIH HHS R01 CA084198NCI NIH HHS R01 CA087869NCI NIH HHS R37 CA084198NCRR NIH HHS UL1 RR025758NICHD NIH HHS R01 HD045022NICHD NIH HHS R37 HD045022PHS HHS R01-HDO45022
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Blotting, SouthernCell Culture TechniquesCells, CulturedCellular ReprogrammingHumansImmunohistochemistryInduced Pluripotent Stem CellsLeukocytes, MononuclearReverse Transcriptase Polymerase Chain ReactionT-Lymphocytes

Identifiers

PMID20621045
PMCPMC2917234

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.