Evidence map›Paper›PMID 20620034›Full record

ArticleColloids and surfaces. B, Biointerfaces2010

Morphological changes of supported lipid bilayers induced by lysozyme: planar domain formation vs. multilayer stacking.

Valeriya M Trusova, Galyna P Gorbenko, Irina Akopova, Julian G Molotkovsky, Ignacy Gryczynski, Julian Borejdo, Zygmunt Gryczynski

Abstract read
In one paragraph

Article in Colloids and surfaces. B, Biointerfaces, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Valeriya M TrusovaDepartment of Biological and Medical Physics, VN Karazin Kharkov National University, 4 Svobody Sq, Kharkov 61077, Ukraine. valtrusova@yahoo.com
Galyna P Gorbenko
Irina Akopova
Julian G Molotkovsky
Ignacy Gryczynski
Julian Borejdo
Zygmunt Gryczynski
University of North Texas · USUniversity of North Texas Health Science Center · USV. N. Karazin Kharkiv National University · UAInstitute of Bioorganic Chemistry · RU

Funding

Novel Fluorophores for Molecular and Cellular ImagingR01EB012003 · NIBIB · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI GRYCZYNSKI, ZYGMUNT, YU, YIHUA BRUCE · 2011 to 2014
$1.8M
NIBIB NIH HHS EB012334NIBIB NIH HHS R01 EB012003
6 · The paper itself

Abstract

Total internal reflection fluorescence microscopy (TIRFM) has been utilized to explore the effect of cationic protein lysozyme (Lz) on the morphology of solid-supported lipid bilayers (SLBs) comprised of zwitterionic lipid phosphatidylcholine (PC) and its mixture with anionic lipid cardiolipin (CL). Kinetic TIRFM imaging of different systems revealed subtle interplay between lipid lateral segregation accompanied by exchange of neutral and acidic lipids in the protein-lipid interaction zone, and the formation of lipid multilayer stacks. The switch between these states was shown to be controlled by CL content. In weakly charged SLBs containing 5 mol% CL, assembling of CL molecules into planar domains upon Lz adsorption has been observed while at higher content of anionic lipid (25 mol%) in-plane domains tend to transform into multilayer stacks, thereby ensuring the most thermodynamically-favorable membrane conformation.

Indexed as

CardiolipinsLipid BilayersMicroscopy, FluorescenceMuramidasePhosphatidylcholinesThermodynamicsCardiolipinsLipid BilayersMuramidasePhosphatidylcholines

Identifiers

PMID20620034
PMCPMC3277818
OpenAlexW2036084674

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.