Evidence map›Paper›PMID 20619867›Full record

ArticleVirology2010

Molecular and physiological analysis of three Pseudomonas aeruginosa phages belonging to the "N4-like viruses".

Pieter-Jan Ceyssens, Andrew Brabban, Larissa Rogge, Matthew Spooner Lewis, Derek Pickard, David Goulding, Gordon Dougan, Jean-Paul Noben, Andrew Kropinski, Elizabeth Kutter and 1 more

Abstract read
In one paragraph

Article in Virology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed.

  1. Article
  2. Balancing of immune activation and suppression during phage infection.bioRxiv : the preprint server for biology · 2026
    Article
  3. Review
  4. Article
  5. mBio · 2026
    Article
  6. Antibiotics (Basel, Switzerland) · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Chitosan-based matrix as a carrier for bacteriophages.Applied microbiology and biotechnology · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pieter-Jan CeyssensDivision of Gene Technology, Katholieke Universiteit Leuven, Kasteelpark Arenberg, Leuven, B-3001, Belgium.
Andrew Brabban
Larissa Rogge
Matthew Spooner Lewis
Derek Pickard
David Goulding
Gordon Dougan
Jean-Paul Noben
Andrew Kropinski
Elizabeth Kutter
Rob Lavigne

Funding

Wellcome Trust
6 · The paper itself

Abstract

We present a detailed analysis of the genome architecture, structural proteome and infection-related properties of three Pseudomonas phages, designated LUZ7, LIT1 and PEV2. These podoviruses encapsulate 72.5 to 74.9 kb genomes and lyse their host after 25 min aerobic infection. PEV2 can successfully infect under anaerobic conditions, but its latent period is tripled, the lysis proceeds far slower and the burst size decreases significantly. While the overall genome structure of these phages resembles the well-studied coliphage N4, these Pseudomonas phages encode a cluster of tail genes which displays significant similarity to a Pseudomonasaeruginosa (cryptic) prophage region. Using ESI-MS/MS, these tail proteins were shown to be part of the phage particle, as well as ten other proteins including a giant 370 kDa virion RNA polymerase. These phages are the first described representatives of a novel kind of obligatory lytic P. aeruginosa-infecting phages, belonging to the widespread "N4-like viruses" genus.

Indexed as

AnimalsGene Expression Regulation, ViralGenome, ViralMolecular Sequence DataPseudomonas aeruginosaPseudomonas PhagesViral Structural ProteinsViral Structural Proteins

Identifiers

PMID20619867
PMCPMC3715699

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.