Evidence map›Paper›PMID 20619847›Full record

ArticleJournal of colloid and interface science2010

Nisin adsorption to polyethylene oxide layers and its resistance to elution in the presence of fibrinogen.

Matthew P Ryder, Karl F Schilke, Julie A Auxier, Joseph McGuire, Jennifer A Neff

Open access · greenAbstract read
In one paragraph

Article in Journal of colloid and interface science, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Concentration effects on peptide elution from pendant PEO layers.Colloids and surfaces. B, Biointerfaces · 2014
    Article
  3. Article
  4. Article
  5. Quantifying nisin adsorption behavior at pendant PEO layers.Journal of colloid and interface science · 2013
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Matthew P RyderSchool of Chemical, Biological and Environmental Engineering, Oregon State University, Corvallis, OR 97331, USA.
Karl F Schilke
Julie A Auxier
Joseph McGuire
Jennifer A Neff
Oregon State University · USAllvivo Vascular (United States) · US

Funding

Peptide Based Antibacterial CoatingR44DK072560 · NIDDK · ALLVIVO VASCULAR, INC. · PI NEFF, JENNIFER ANN · 2007 to 2013
$3.8M
NIDDK NIH HHS 2 R44 DK 072560-02NIDDK NIH HHS R44 DK072560
6 · The paper itself

Abstract

The adsorption and elution of the antimicrobial peptide nisin at silanized silica surfaces coated to present pendant polyethylene oxide chains was detected in situ by zeta potential measurements. Silica microspheres were treated with trichlorovinylsilane to introduce hydrophobic vinyl groups, followed by self assembly of the polyethylene oxide-polypropylene oxide-polyethylene oxide (PEO-PPO-PEO) triblock surfactant Pluronic F108, or an F108 derivative with nitrilotriacetic acid end groups. Triblock-coated microspheres were gamma-irradiated to covalently stabilize the PPO-surface association. PEO layer stability was evaluated by triblock resistance to elution by SDS, and layer uniformity was evaluated by fibrinogen repulsion. Introduction of nisin to uncoated or triblock-coated microspheres produced a significant positive change in surface charge (zeta potential) as a result of adsorption of the cationic peptide. In sequential adsorption experiments, the introduction of fibrinogen to nisin-loaded triblock layers caused a decrease in zeta potential that was consistent with partial elution of nisin and/or preferential location of fibrinogen at the interface. This change was substantially more pronounced for uncoated than triblock-coated silica, indicating that the PEO layer offers enhanced resistance to nisin elution.

Indexed as

AdsorptionAnti-Bacterial AgentsEnzyme-Linked Immunosorbent AssayFibrinogenHydrophobic and Hydrophilic InteractionsNisinPolyethylene GlycolsAnti-Bacterial AgentsFibrinogenNisinPolyethylene Glycols

Identifiers

PMID20619847
PMCPMC2918692
OpenAlexW2045584972

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.