ArticleNeurogastroenterology and motility2010
Origin, propagation and regional characteristics of porcine gastric slow wave activity determined by high-resolution mapping.
Article in Neurogastroenterology and motility, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
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Who cites it
59 citing papers in PubMed, 113 citations in OpenAlex.
- Optical Mapping of Pacing-Elicited Slow Waves in the Swine Stomach: Role of Virtual Electrodes.Neurogastroenterology and motility · 2026Article
- Detailed microCT imaging protocol for ex vivo rat stomachs with comparative analysis.Scientific reports · 2025Article
- Influence of isoflurane and propofol on gastric slow wave patterns and pacing efficacy in pigs.American journal of physiology. Gastrointestinal and liver physiology · 2025Article
- Simultaneous optical imaging of gastric slow waves and contractions in the in vivo porcine stomach.American journal of physiology. Gastrointestinal and liver physiology · 2024Article
- A novel compartmental approach for modeling stomach motility and gastric emptying.Computers in biology and medicine · 2024Article
- Mapping the rat gastric slow-wave conduction pathway: bridging in vitro and in vivo methods, revealing a loosely coupled region in the distal stomach.American journal of physiology. Gastrointestinal and liver physiology · 2024Article
- Optimization of pacing parameters to entrain slow wave activity in the pig jejunum.Scientific reports · 2024Article
- Neural regulation of slow waves and phasic contractions in the distal stomach: a mathematical model.Journal of neural engineering · 2024Article
- High-resolution in vivo monophasic gastric slow waves to quantify activation and recovery profiles.Neurogastroenterology and motility · 2022Article
- In vivo experimental validation of detection of gastric slow waves using a flexible multichannel electrogastrography sensor linear array.Biomedical engineering online · 2022Article
- Targeted ablation of gastric pacemaker sites to modulate patterns of bioelectrical slow wave activation and propagation in an anesthetized pig model.American journal of physiology. Gastrointestinal and liver physiology · 2022Article
- Gastric ablation as a novel technique for modulating electrical conduction in the in vivo stomach.American journal of physiology. Gastrointestinal and liver physiology · 2021Article
- Strategies to Refine Gastric Stimulation and Pacing Protocols: Experimental and Modeling Approaches.Frontiers in neuroscience · 2021Review
- High-resolution Mapping of Hyperglycemia-induced Gastric Slow Wave Dysrhythmias.Journal of neurogastroenterology and motility · 2019Article
- Temporary Gastric Stimulation in Patients With Gastroparesis Symptoms: Low-Resolution Mapping Multiple Versus Single Mucosal Lead Electrograms.Gastroenterology research · 2019Article
- High-resolution optical mapping of gastric slow wave propagation.Neurogastroenterology and motility · 2019Article
- High-resolution electrical mapping of porcine gastric slow-wave propagation from the mucosal surface.Neurogastroenterology and motility · 2017Article
- Time-Delay Mapping of High-Resolution Gastric Slow-Wave Activity.IEEE transactions on bio-medical engineering · 2017Article
- Progress in Mathematical Modeling of Gastrointestinal Slow Wave Abnormalities.Frontiers in physiology · 2017Review
- A novel retractable laparoscopic device for mapping gastrointestinal slow wave propagation patterns.Surgical endoscopy · 2017Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 3 countries.
Funding
Abstract
backgroundThe pig is a popular model for gastric electrophysiology studies. However, its normal baseline gastric activity has not been well characterized. High-resolution (HR) mapping has recently enabled an accurate description of human and canine gastric slow wave activity, and was employed here to define porcine gastric slow wave activity.
methodsFasted pigs underwent HR mapping following anesthesia and laparotomy. Flexible printed-circuit-board arrays were used (160-192 electrodes; spacing 7.62 mm). Anterior and posterior surfaces were mapped simultaneously. Activation times, velocities, amplitudes and frequencies were calculated, and regional differences evaluated. KEY
resultsMean slow wave frequency was 3.22 ± 0.23 cpm. Slow waves propagated isotropically from the pacemaker site (greater curvature, mid-fundus). Pacemaker activity was of higher velocity (13.3 ± 1.0 mm s(-1)) and greater amplitude (1.3 ± 0.2 mV) than distal fundal activity (9.0 ± 0.6 mm s(-1), 0.9 ± 0.1 mV; P < 0.05). Velocities and amplitudes were similar in the distal fundus, proximal corpus (8.4 ± 0.8 mm s(-1), 1.0 ± 0.1 mV), distal corpus (8.3 ± 0.8 mm s(-1), 0.9 ± 0.2 mV) and antrum (6.8 ± 0.6 mm s(-1), 1.1 ± 0.2 mV). Activity was continuous across the anterior and posterior gastric surfaces. CONCLUSIONS & INFERENCES: This study has quantified normal porcine gastric slow wave activity at HR during anesthesia and laparotomy. The pacemaker region was associated with high-amplitude, high-velocity slow wave activity compared to the activity in the rest of the stomach. The increase in distal antral slow wave velocity and amplitude previously described in canines and humans is not observed in the pig. Investigators should be aware of these inter-species differences.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.