Evidence map›Paper›PMID 20617940›Full record

ReviewAnnual review of biomedical engineering2010

Microscopic imaging and spectroscopy with scattered light.

Nada N Boustany, Stephen A Boppart, Vadim Backman

Abstract readReview
In one paragraph

Review in Annual review of biomedical engineering, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Article
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  6. Review
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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nada N BoustanyDepartment of Biomedical Engineering, Rutgers University, Piscataway, New Jersey 08854, USA. nboustan@rci.rutgers.edu
Stephen A Boppart
Vadim Backman

Funding

Novel Biophotonics Methodology for Colon Cancer ScreeningR01CA128641 · NCI · NORTHWESTERN UNIVERSITY · PI BACKMAN, VADIM · 2008 to 2012
$7.3M
Mechanisms of Light Scattering in Living TissuesR01EB003682 · NIBIB · NORTHWESTERN UNIVERSITY · PI BACKMAN, VADIM, PRADHAN, PRABHAKAR · 2005 to 2013
$2.2M
Magnetomotive Optical Molecular Imaging Probes (RMI)R21EB005321 · NIBIB · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI BOPPART, STEPHEN A · 2005 to 2008
$1.5M
Optical Coherence Tomography Image-Guided Surgical Resection of Solid TumorsR01EB005221 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BOPPART, STEPHEN A · 2006 to 2009
$1.3M
NCI NIH HHS R01 CA128641NIBIB NIH HHS R01 EB003682NIBIB NIH HHS R01 EB005221NIBIB NIH HHS R21 EB005321
6 · The paper itself

Abstract

Optical contrast based on elastic scattering interactions between light and matter can be used to probe cellular structure, cellular dynamics, and image tissue architecture. The quantitative nature and high sensitivity of light scattering signals to subtle alterations in tissue morphology, as well as the ability to visualize unstained tissue in vivo, has recently generated significant interest in optical-scatter-based biosensing and imaging. Here we review the fundamental methodologies used to acquire and interpret optical scatter data. We report on recent findings in this field and present current advances in optical scatter techniques and computational methods. Cellular and tissue data enabled by current advances in optical scatter spectroscopy and imaging stand to impact a variety of biomedical applications including clinical tissue diagnosis, in vivo imaging, drug discovery, and basic cell biology.

Indexed as

LightScattering, RadiationCellsHumansMicroscopySpectrum Analysis

Identifiers

PMID20617940
PMCPMC3357207

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.