ArticleJournal of the American Chemical Society2010
Protein and small molecule recognition properties of deep cavitands in a supported lipid membrane determined by calcination-enhanced SPR spectroscopy.
Article in Journal of the American Chemical Society, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 54 citations in OpenAlex.
- Acridane[4]Arenes: Scope of the Macro-Tetramerization, Derivatization Options, and Water-Soluble Derivatives.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Article
- Selective Recognition of Amino Acids and Peptides by Small Supramolecular Receptors.Molecules (Basel, Switzerland) · 2020Review
- Lipid bilayer environments control exchange kinetics of deep cavitand hosts and enhance disfavored guest conformations.Chemical science · 2018Article
- Calixarene-mediated liquid membrane transport of choline conjugates 3: The effect of handle variation on neurotransmitter transport.Bioorganic & medicinal chemistry letters · 2017Article
- Selective protein recognition in supported lipid bilayer arrays by tailored, dual-mode deep cavitand hosts.Soft matter · 2017Article
- Cell and Protein Recognition at a Supported Bilayer Interface via In Situ Cavitand-Mediated Functional Polymer Growth.Langmuir : the ACS journal of surfaces and colloids · 2015Article
- Calixarene-Mediated Liquid Membrane Transport of Choline Conjugates 2: Transport of Drug-Choline Conjugates and Neurotransmitters.European journal of organic chemistry · 2015Article
- Labeled protein recognition at a membrane bilayer interface by embedded synthetic receptors.Langmuir : the ACS journal of surfaces and colloids · 2014Article
- Calixarene-Mediated Liquid-Membrane Transport of Choline Conjugates.European journal of organic chemistry · 2014Article
- Selective cavitand-mediated endocytosis of targeted imaging agents into live cells.Journal of the American Chemical Society · 2013Article
- Article
- Embedding resorcinarene cavitands in lipid vesicles().New journal of chemistry = Nouveau journal de chimie · 2012Article
- 4,6,10,12,16,18,22,24-Octa-O-methyl-2,8,14,20-tetra-pentylresorcin[4]arene.Acta crystallographica. Section E, Structure reports online · 2011Article
- Sensitivity Comparison of Surface Plasmon Resonance and Plasmon-Waveguide Resonance Biosensors.Sensors and actuators. B, Chemical · 2011Article
- Interface design and multiplexed analysis with surface plasmon resonance (SPR) spectroscopy and SPR imaging.The Analyst · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
This paper details the incorporation of a water-soluble deep cavitand into a membrane bilayer assembled onto a nanoglassified surface for study of molecular recognition in a membrane-mimicking setting. The cavitand retains its host properties, and real-time analysis of the host:guest properties of the membrane:cavitand complex via surface plasmon resonance and fluorescence microscopy is described. The host shows selectivity for choline-derived substrates, and no competitive incorporation of substrate is observed in the membrane bilayer. A variety of trimethylammonium-derived substrates are suitable guests, displaying varied binding affinities in a millimolar range. The membrane:cavitand:guest complexes can be subsequently used to capture NeutrAvidin protein at the membrane surface if a biotin-derived guest molecule is used. The surface coverage of NeutrAvidin is affected by the spacer used to derivatize the biotin. Increased distance from the bilayer allows a higher concentration of protein to be immobilized, suggesting a diminishing detrimental steric effect when the binding event is shifted away from the surface.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.