ReviewMolecular imaging and biology2011
Optical image-guided surgery--where do we stand?
Review in Molecular imaging and biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07438860 (Fluorescence-Guided Imaging of Brain Tumors), which is not on this map. Cited by 113 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Fluorescence-Guided Imaging of Brain Tumors: A Safety Study Using SBK2- ICG in a Phase 1 Clinical Trial
Who cites it
113 citing papers in PubMed, 2 syntheses or guidelines pooled it, 270 citations in OpenAlex.
- Novel real-time optical imaging modalities for the detection of neoplastic lesions in urology: a systematic review.Surgical endoscopy · 2019Pooled it
- The clinical usefulness of optical coherence tomography during cancer interventions.Journal of cancer research and clinical oncology · 2018Pooled it
- Near-infrared fluorescence imaging in patients undergoing pancreaticoduodenectomy.European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes · 2011Trial
- Near-infrared fluorescence imaging for ureteral and sentinel lymph node mapping in gynecological minimally invasive surgery: a review of fluorophores and domestic laparoscopic systems.World journal of surgical oncology · 2026Review
- Bridging preclinical and clinical fluorescence-guided surgery with advanced cancer vision goggles.Npj imaging · 2026Article
- Tumour Marker Expression in Head and Neck Malignancies to Identify Potential Targets for Intraoperative Molecular Near-Infrared Imaging.Molecular diagnosis & therapy · 2024Article
- Cationic fluorinated micelles for cell labeling andScientific reports · 2024Article
- Advances of surgical robotics: image-guided classification and application.National science review · 2024Review
- Multispectral fluorescence imaging of EGFR and PD-L1 for precision detection of oral squamous cell carcinoma: a preclinical and clinical study.BMC medicine · 2024Article
- Article
- Robust H-K Curvature Map Matching for Patient-to-CT Registration in Neurosurgical Navigation Systems.Sensors (Basel, Switzerland) · 2023Article
- In Vitro Antibody Quantification with Hyperspectral Imaging in a Large Field of View for Clinical Applications.Bioengineering (Basel, Switzerland) · 2023Article
- Quantifying the Impact of Signal-to-background Ratios on Surgical Discrimination of Fluorescent Lesions.Molecular imaging and biology · 2023Article
- The current status and future prospects for molecular imaging-guided precision surgery.Cancer imaging : the official publication of the International Cancer Imaging Society · 2022Review
- The complementary value of intraoperative fluorescence imaging and Raman spectroscopy for cancer surgery: combining the incompatibles.European journal of nuclear medicine and molecular imaging · 2022Review
- A novel tool for visualization and detection of pancreatic neuroendocrine tumours. A 'fluorescent' world is calling for exploration?Przeglad menopauzalny = Menopause review · 2021Review
- Introducing Fluorescence-Guided Surgery for Pediatric Ewing, Osteo-, and Rhabdomyosarcomas: A Literature Review.Biomedicines · 2021Review
- Enhancement of signal-to-noise ratio for fluorescence endoscope image based on fast digital lock-in algorithm.Royal Society open science · 2021Article
- A two-in-one Janus NIR-II AIEgen with balanced absorption and emission for image-guided precision surgery.Materials today. Bio · 2021Article
- Application of atomic force microscope in diagnosis of single cancer cells.Biomicrofluidics · 2020Review
53 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In cancer surgery, intra-operative assessment of the tumor-free margin, which is critical for the prognosis of the patient, relies on the visual appearance and palpation of the tumor. Optical imaging techniques provide real-time visualization of the tumor, warranting intra-operative image-guided surgery. Within this field, imaging in the near-infrared light spectrum offers two essential advantages: increased tissue penetration of light and an increased signal-to-background-ratio of contrast agents. In this article, we review the various techniques, contrast agents, and camera systems that are currently used for image-guided surgery. Furthermore, we provide an overview of the wide range of molecular contrast agents targeting specific hallmarks of cancer and we describe perspectives on its future use in cancer surgery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.