Evidence map›Paper›PMID 20617237›Full record

ArticleChemical communications (Cambridge, England)2010

Selective fluorescence detection of cysteine and N-terminal cysteine peptide residues.

Soojin Lim, Jorge O Escobedo, Mark Lowry, Xiangyang Xu, Robert Strongin

Open access · greenAbstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 113 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Fluorescent Probes for Live Cell Thiol Detection.Molecules (Basel, Switzerland) · 2021
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Detecting specific saccharides via a single indicator.Chemical communications (Cambridge, England) · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Soojin LimDepartment of Chemistry, Portland State University, Portland, Oregon 97207, USA.
Jorge O Escobedo
Mark Lowry
Xiangyang Xu
Robert Strongin
Portland State University · US

Funding

Synthesis and Study of Novel Sensing AgentsR01EB002044 · NIBIB · PORTLAND STATE UNIVERSITY · PI STRONGIN, ROBERT M · 2003 to 2010
$1.6M
NIBIB NIH HHS R01 EB002044
6 · The paper itself

Abstract

A new fluorogenic fluorescein derivative containing an alpha,beta-unsaturated aldehyde moiety produces a selective fluorescent signal enhancement in the presence of cysteine or peptides containing N-terminal cysteine residues. The mechanism is based on synergistic covalent and supramolecular interactions.

Indexed as

AldehydesCysteinePeptidesSpectrometry, FluorescenceAldehydesCysteinePeptides

Identifiers

PMID20617237
PMCPMC3376164
OpenAlexW2050063976

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.