Evidence map›Paper›PMID 20617216›Full record

ReviewCanadian respiratory journal

Rare lung diseases III: pulmonary Langerhans' cell histiocytosis.

Stephen C Juvet, David Hwang, Gregory P Downey

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Canadian respiratory journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 50 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Stephen C JuvetDivision of Respirology and Clinician-Scientist Training Program, Department of Medicine, Toronto General Hospital/University Health Network, Toronto, Ontario, Canada.
David Hwang
Gregory P Downey
Toronto General Hospital · CAUniversity Health Network · CAUniversity of Colorado Anschutz Medical Campus · US

Funding

Focal Adhesion Modulation of IL-1 Signaling: Importance in Pulmonary FibrosisR01HL090669 · NHLBI · NATIONAL JEWISH HEALTH · PI DOWNEY, GREGORY PAUL · 2008 to 2011
$1.8M
NHLBI NIH HHS HL090669NHLBI NIH HHS R01 HL090669
6 · The paper itself

Abstract

Pulmonary Langerhans' cell histiocytosis (PLCH) is an unusual cystic lung disease that is also characterized by extrapulmonary manifestations. The current review discusses the presenting features and relevant diagnostic testing and treatment options for PLCH in the context of a clinical case. While the focus of the present article is adult PLCH and its pulmonary manifestations, it is important for clinicians to distinguish the adult and pediatric forms of the disease, as well as to be alert for possible extrapulmonary complications. A major theme of the current series of articles on rare lung diseases has been the translation of insights gained from fundamental research to the clinic. Accordingly, the understanding of dendritic cell biology in this disease has led to important advances in the care of patients with PLCH.

Indexed as

AdultFemaleHistiocytosis, Langerhans-CellHumansLungTomography, X-Ray Computed

Identifiers

PMID20617216
PMCPMC2900147
OpenAlexW133654034

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.