Evidence map›Paper›PMID 20617167›Full record

ArticlePLoS pathogens2010

Identification of GBV-D, a novel GB-like flavivirus from old world frugivorous bats (Pteropus giganteus) in Bangladesh.

Jonathan H Epstein, Phenix-Lan Quan, Thomas Briese, Craig Street, Omar Jabado, Sean Conlan, Shahneaz Ali Khan, Dawn Verdugo, M Jahangir Hossain, Stephen K Hutchison and 4 more

Open access · goldAbstract read
In one paragraph

Article in PLoS pathogens, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 74 citations in OpenAlex.

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  16. Bat research takes wing.Lab animal · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Jonathan H EpsteinConservation Medicine Program, Wildlife Trust, New York, New York, United States of America.
Phenix-Lan Quan
Thomas Briese
Craig Street
Omar Jabado
Sean Conlan
Shahneaz Ali Khan
Dawn Verdugo
M Jahangir Hossain
Stephen K Hutchison
Michael Egholm
Stephen P Luby
Peter Daszak
W Ian Lipkin
Columbia University · USEcoHealth Alliance · USInternational Centre for Diarrhoeal Disease Research · BD

Funding

Viral Pathogenesis and TherapeuticsU54AI057158 · NIAID · WADSWORTH CENTER · PI LEVY, DAVID E · 2003 to 2014
$100.8M
The Ecology, Emergence and Pandemic Potential of Nipah virus in BangladeshR01TW005869 · FIC · WILDLIFE TRUST · PI DASZAK, PETER · 2002 to 2012
$5.5M
Viral Arrays for BiodefenseU01AI070411 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LIPKIN, W. IAN · 2006 to 2010
$4.4M
Risk of Viral Emergence from BatsR01AI079231 · NIAID · ECOHEALTH ALLIANCE, INC. · PI DASZAK, PETER · 2008 to 2012
$2.6M
Risk for Future Outbreaks of Henipaviruses in South AsiaK08AI067549 · NIAID · ECOHEALTH ALLIANCE, INC. · PI EPSTEIN, JONATHAN H · 2007 to 2010
$574k
FIC NIH HHS R01 TW005869NIAID NIH HHS AI070411NIAID NIH HHS AI079231NIAID NIH HHS AI57158NIAID NIH HHS K08 AI067549NIAID NIH HHS K08AI067549NIAID NIH HHS R01 AI079231NIAID NIH HHS U01 AI070411NIAID NIH HHS U54 AI057158
6 · The paper itself

Abstract

Bats are reservoirs for a wide range of zoonotic agents including lyssa-, henipah-, SARS-like corona-, Marburg-, Ebola-, and astroviruses. In an effort to survey for the presence of other infectious agents, known and unknown, we screened sera from 16 Pteropus giganteus bats from Faridpur, Bangladesh, using high-throughput pyrosequencing. Sequence analyses indicated the presence of a previously undescribed virus that has approximately 50% identity at the amino acid level to GB virus A and C (GBV-A and -C). Viral nucleic acid was present in 5 of 98 sera (5%) from a single colony of free-ranging bats. Infection was not associated with evidence of hepatitis or hepatic dysfunction. Phylogenetic analysis indicates that this first GBV-like flavivirus reported in bats constitutes a distinct species within the Flaviviridae family and is ancestral to the GBV-A and -C virus clades.

Indexed as

AnimalsBangladeshChiropteraDNA, ViralFlaviviridaeGB virus AGB virus CPhylogenySequence Homology, Nucleic AcidDNA, Viral

Identifiers

PMID20617167
PMCPMC2895649
OpenAlexW2161253094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.