ReviewSaudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
Cardiovascular changes in cirrhosis: pathogenesis and clinical implications.
Review in Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04909645 (A Comparison of Invasive and Non-invasive Measurement of Cardiac Index and Systemic Vascular Resistance in Living Donor Liver Transplantation), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Comparison of Invasive and Non-invasive Measurement of Cardiac Index and Systemic Vascular Resistance in Living Donor Liver Transplantation
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Liver cirrhosis and left ventricle diastolic dysfunction: Systematic review.World journal of gastroenterology · 2019Pooled it
- Macrophage Inhibitory Factor in Myocardial Oxidative Stress and Inflammation During Thioacetamide-Induced Liver Fibrosis: Modulation by Betaine.Current issues in molecular biology · 2025Article
- Liver and systemic hemodynamics in cirrhotic children.World journal of hepatology · 2025Review
- The Assessment of Cardiovascular Abnormalities in Patients With Chronic Liver Disease: A Cross-Sectional Study.Cureus · 2024Article
- Exercise Training Attenuates Cirrhotic Cardiomyopathy.Journal of cardiovascular translational research · 2021Article
- qSOFA score not predictive of in-hospital mortality in emergency patients with decompensated liver cirrhosis.Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2019Observational
- [Anesthesiological aspects of liver transplantation].Der Anaesthesist · 2019Article
- Inferolateral ST-segment elevation with use of Sengstaken-Blakemore tube for variceal bleeding during orthotopic liver transplantation.BMJ case reports · 2019Article
- Approach to the liver transplant early postoperative period: an institutional standpoint.Revista Brasileira de terapia intensivaReview
- Cardiovascular dysfunction in patients with liver cirrhosis.Annals of gastroenterologyReview
- Morphological Cardiac Alterations in Liver Cirrhosis: An Autopsy Study.Heart views : the official journal of the Gulf Heart AssociationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Liver cirrhosis is associated with a wide range of cardiovascular abnormalities including hyperdynamic circulation, cirrhotic cardiomyopathy, and pulmonary vascular abnormalities. The pathogenic mechanisms of these cardiovascular changes are multifactorial and include neurohumoral and vascular dysregulations. Accumulating evidence suggests that cirrhosis-related cardiovascular abnormalities play a major role in the pathogenesis of multiple life-threatening complications including hepatorenal syndrome, ascites, spontaneous bacterial peritonitis, gastroesophageal varices, and hepatopulmonary syndrome. Treatment targeting the circulatory dysfunction in these patients may improve the short-term prognosis while awaiting liver transplantation. Careful fluid management in the immediate post-transplant period is extremely important to avoid cardiac-related complications. Liver transplantation results in correction of portal hypertension and reversal of all the pathophysiological mechanisms that lead to the cardiovascular abnormalities, resulting in restoration of a normal circulation. The following is a review of the pathogenesis and clinical implications of the cardiovascular changes in cirrhosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.