ArticleProceedings of the National Academy of Sciences of the United States of America2010
From the Cover: Neurons in the anterior olfactory nucleus pars externa detect right or left localization of odor sources.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
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Who cites it
63 citing papers in PubMed, 109 citations in OpenAlex.
- Simultaneous detection and estimation in olfactory sensing.bioRxiv : the preprint server for biology · 2025Article
- Mice navigate scent trails using predictive policies.bioRxiv : the preprint server for biology · 2025Article
- Article
- Stereo olfaction underlies stable coding of head direction in blind mice.Nature communications · 2025Article
- Odor localization in structural interhemispheric deficits.Chemical senses · 2025Article
- Discriminating Parkinson's disease patients from healthy controls using nasal respiratory airflow.Communications medicine · 2024Article
- Article
- How do mammals convert dynamic odor information into neural maps for landscape navigation?PLoS biology · 2024Article
- Olfactory-trigeminal integration in the primary olfactory cortex.Human brain mapping · 2024Article
- Common principles for odour coding across vertebrates and invertebrates.Nature reviews. Neuroscience · 2024Review
- Imbalance inInternational journal of molecular sciences · 2024Article
- Odors in space.Frontiers in neural circuits · 2024Review
- Olfactory information processing viewed through mitral and tufted cell-specific channels.Frontiers in neural circuits · 2024Review
- Recruitment of grid-like responses in human entorhinal and piriform cortices by odor landmark-based navigation.Current biology : CB · 2023Article
- Heterogeneous Damage to the Olfactory Epithelium in Patients with Post-Viral Olfactory Dysfunction.Journal of clinical medicine · 2023Article
- Long-range functional loops in the mouse olfactory system and their roles in computing odor identity.Neuron · 2022Article
- Article
- Lessons from behavioral lateralization in olfaction.Brain structure & function · 2022Review
- Active sensing in a dynamic olfactory world.Journal of computational neuroscience · 2022Article
- Using your nose to find your way: Ethological comparisons between human and non-human species.Neuroscience and biobehavioral reviews · 2021Review
3 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rodents can localize odor sources by comparing odor inputs to the right and left nostrils. However, the neuronal circuits underlying such odor localization are not known. We recorded neurons in the anterior olfactory nucleus (AON) while administering odors to the ipsilateral or contralateral (ipsi- or contra-) nostril. Neurons in the AON pars externa (AONpE) showed respiration phase-locked excitatory spike responses to ipsinostril-only stimulation with a category of odorants, and inhibitory responses to contranostril-only stimulation with the same odorants. Simultaneous odor stimulation of the ipsi- and contranostrils elicited significantly smaller responses than ipsinostril-only stimulation, indicating that AONpE neurons subtract the contranostril odor inputs from ipsinostril odor inputs. An ipsilateral odor source induced larger responses than a centrally located source, whereas an odor source at the contralateral position elicited inhibitory responses. These results indicate that individual AONpE neurons can distinguish the right or left position of an odor source by referencing signals from the two nostrils.
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