Evidence map›Paper›PMID 20615615›Full record

ArticlePain2010

Functional abdominal pain in childhood and adolescence increases risk for chronic pain in adulthood.

Lynn S Walker, Christine M Dengler-Crish, Sara Rippel, Stephen Bruehl

Open access · greenAbstract read
In one paragraph

Article in Pain, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 126 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
126citing papers in PubMed, 1 pooled it
12.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

126 citing papers in PubMed, 1 synthesis or guideline pooled it, 255 citations in OpenAlex.

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66 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Lynn S WalkerVanderbilt University School of Medicine and the Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, USA Vanderbilt Kennedy Center for Research on Human Development, Nashville, TN, USA Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, TN, USA.
Christine M Dengler-Crish
Sara Rippel
Stephen Bruehl
Monroe Carell Jr. Children's Hospital · USVanderbilt University · US

Funding

YOHIMBINE AS A MODEL OF ORTHOSTATIC INTOLERANCEM01RR000095 · NCRR · VANDERBILT UNIVERSITY · PI DRAKE, WONDER P. · 1985 to 2008
$38.3M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
THREE-TIERED PREVENTION MODEL TO BETTER SERVE ALL STUDENP30HD015052 · NICHD · VANDERBILT UNIVERSITY · PI DYKENS, ELISABETH MAY · 1985 to 2014
$18.6M
TRAINING IN GASTROENTEROLOGYT32DK007673 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 1992 to 2026
$8.4M
ILLNESS BEHAVIOR AND SOMATIZATION IN CHILDRENR01HD023264 · NICHD · VANDERBILT UNIVERSITY · PI WALKER, LYNN D. · 1987 to 2011
$3.9M
Pain Regulatory Dysfunction in Chronic PainR01NS046694 · NINDS · VANDERBILT UNIVERSITY · PI BRUEHL, STEPHEN · 2004 to 2007
$1.4M
NCRR NIH HHS M01 RR000095NCRR NIH HHS M01 RR-00095NICHD NIH HHS P30 HD015052NICHD NIH HHS P30 HD15052NICHD NIH HHS R01 HD023264NICHD NIH HHS R01 HD23264NIDDK NIH HHS DK058404NIDDK NIH HHS P30 DK058404NIDDK NIH HHS T32 DK007673NIDDK NIH HHS T32DK007673NINDS NIH HHS R01 NS046694NINDS NIH HHS R01NS046694
6 · The paper itself

Abstract

A few studies of long-term outcomes for pediatric functional abdominal pain (FAP) have assessed acute non-abdominal pain at follow-up, but none has assessed chronic pain. We followed a cohort of pediatric patients with FAP (n=155) and a well control group (n=45) prospectively for up to 15 years. Participants ranged in age from 18 to 32 years at a follow-up telephone interview. FAP patients were classified as Resolved (n=101) versus Unresolved (n=54) at follow-up, based on whether they reported symptoms consistent with the adult Rome III criteria for a functional gastrointestinal disorder. Headache symptoms and reports of chronic non-abdominal pain also were assessed at follow-up. In the Unresolved group, 48.1% reported one or more sites of chronic non-abdominal pain at follow-up, compared to 24.7% in the Resolved group and 13.3% in the control group, p<0.01. More than half (57.4%) of the Unresolved group endorsed symptoms consistent with International Headache Society criteria for headache, compared to 44.6% of the Resolved group and 31% of controls, p<0.05. One-third of the Unresolved group reported both headache and one or more sites of chronic non-abdominal pain at follow-up, compared to 17.8% of the Resolved group and 4.4% of controls. Youth with FAP that persists into adulthood may be at increased risk for chronic pain and headache. Examination of central mechanisms that are common across chronic pain disorders may enhance understanding of this subgroup of FAP.

Indexed as

Abdominal PainAdolescentAdultChronic DiseaseFemaleHeadacheHumansInterviews as TopicLongitudinal StudiesMalePainPain MeasurementPrevalenceRisk FactorsYoung Adult

Identifiers

PMID20615615
PMCPMC3040563
OpenAlexW2006127599

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.