ArticleJournal of biomechanics2010
Assessment of the bilateral asymmetry of human femurs based on physical, densitometric, and structural rigidity characteristics.
Article in Journal of biomechanics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Multifaceted Preprocessing Optimization for Post-Mortem Radiomics Analysis: A Pilot Study on Forensic Age Estimation Using Proximal Femur Radiomics.Journal of imaging informatics in medicine · 2026Article
- Statistical shape modeling of the proximal femur bone for hip implant design optimization.Scientific reports · 2026Article
- Sex and age specific bone mineral density trends in Sri Lankan adults support the need for normative reference data.Frontiers in endocrinology · 2026Article
- Estrogen loss activates memory T-cells to compromise bone integrity through distinct cortical compartments in mice.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025Article
- Article
- Normative Data of Ulnar Length in Pediatric Indian Population.Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India · 2024Article
- Hip Axis Length and Femoral Neck-Shaft Angle as Risk Factors for Proximal Femur Fractures in Octogenarians to Centenarians.Journal of clinical medicine · 2024Article
- Computed tomography-based structural rigidity analysis can assess tumor- and treatment-induced changes in rat bones with metastatic lesions.BMC cancer · 2024Article
- Proximal femur fracture detection on plain radiography via feature pyramid networks.Scientific reports · 2024Article
- Lower leg symmetry: a Q3D-CT analysis.Surgical and radiologic anatomy : SRA · 2022Article
- Bony asymmetry in patellofemoral morphology and risk factors of instability are mostly clinically negligible.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2021Article
- Body-Worn IMU Human Skeletal Pose Estimation Using a Factor Graph-Based Optimization Framework.Sensors (Basel, Switzerland) · 2020Article
- Bilateral symmetry of the subtalar joint facets and the relationship between the morphology and osteoarthritic changes.Clinical anatomy (New York, N.Y.) · 2020Article
- Volume fusion of CT images to measure femoral symmetricity.Surgical and radiologic anatomy : SRA · 2020Article
- Odontoid Process and Femur: A Novel Bond in Anatomy.Cureus · 2020Article
- Article
- Three-dimensional analysis of shape variations and symmetry of the fibula, tibia, calcaneus and talus.Journal of anatomy · 2019Article
- The medial femoral wall can play a more important role in unstable intertrochanteric fractures compared with lateral femoral wall: a biomechanical study.Journal of orthopaedic surgery and research · 2017Article
- An exploratory study into measuring the cortical bone thickness from CT in the presence of metal implants.International journal of computer assisted radiology and surgery · 2017Article
- Left-right differences in the proximal femur's strength of post-menopausal women: a multicentric finite element study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The purpose of this study was to perform a comprehensive geometric, densitometric, biomechanical, and statistical analysis of paired femurs for an adult population over a wide age range using three imaging modalities to quantify the departure from symmetry in size, bone mineral density, and cross-sectional structural rigidities. Femur measurements were obtained from 20 pairs of cadaveric femurs. Dimensions of these anatomic sites were measured using calipers directly on the bone and plain radiographs. Dual energy X-ray absorptiometry was used to measure bone mineral density. Bone mineral content and axial and bending rigidities were determined from the CT imaging. No differences were observed between the geometric measurements, DXA based bone mineral density and axial and bending rigidities of left and right femurs (P>0.05 for all cases). Left and right proximal femurs are not significantly different based on geometric, densitometric, and structural rigidity measurements. However, absolute left-right differences for individual patients can be substantial. When using the contralateral femur as a control, the number of femur pairs required to assess significant changes in anatomic dimensions and structural properties induced by a tumor, infection, fracture, or implanted device can range from 3 to 165 pairs depending on the desired effect size or sensitivity (5% or 10% difference). This information is important both for femoral arthroplasty implant design and the use of the contralateral femur as an intra-subject control for clinical assessment and research studies. In addition, our statistical analysis provides sample size estimates for planning future orthopedic research studies.
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