ArticleJournal of neurogenetics2010
Application for the Drosophila ventral nerve cord standard in neuronal circuit reconstruction and in-depth analysis of mutant morphology.
Article in Journal of neurogenetics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Frazzled/DCC Regulates Gap Junction Formation at aeNeuro · 2025Article
- Tyrosyl-tRNA synthetase has a noncanonical function in actin bundling.Nature communications · 2023Article
- Transcriptional dysregulation by a nucleus-localized aminoacyl-tRNA synthetase associated with Charcot-Marie-Tooth neuropathy.Nature communications · 2019Article
- Males, the Wrongly Neglected Partners of the Biologically Unprecedented Male-Female Interaction of Schistosomes.Frontiers in genetics · 2019Article
- A Role forFrontiers in cellular neuroscience · 2019Article
- An ankyrin-binding motif regulates nuclear levels of L1-type neuroglian and expression of the oncogeneThe Journal of biological chemistry · 2018Article
- Fragile X Mental Retardation Protein Restricts Small Dye Iontophoresis Entry into Central Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Fragile X Mental Retardation Protein Regulates Activity-Dependent Membrane Trafficking andFrontiers in molecular neuroscience · 2017Review
- Lissencephaly-1 dependent axonal retrograde transport of L1-type CAM Neuroglian in the adult drosophila central nervous system.PloS one · 2017Article
- Structure-function analyses of tyrosine phosphatase PTP69D in giant fiber synapse formation of Drosophila.Molecular and cellular neurosciences · 2015Article
- CMT-associated mutations in glycyl- and tyrosyl-tRNA synthetases exhibit similar pattern of toxicity and share common genetic modifiers in Drosophila.Neurobiology of disease · 2014Article
- Netrin and Frazzled regulate presynaptic gap junctions at a Drosophila giant synapse.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Transsynaptic coordination of synaptic growth, function, and stability by the L1-type CAM Neuroglian.PLoS biology · 2013Article
- Differential effects of human L1CAM mutations on complementing guidance and synaptic defects in Drosophila melanogaster.PloS one · 2013Article
- Whole mount preparation of the adult Drosophila ventral nerve cord for giant fiber dye injection.Journal of visualized experiments : JoVE · 2011Article
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2 authors.
Funding
Abstract
The Drosophila standard brain has been a useful tool that provides information about position and size of different brain structures within a wild-type brain and allows the comparison of imaging data that were collected from individual preparations. Therefore the standard can be used to reveal and visualize differences of brain regions between wild-type and mutant brains and can provide spatial description of single neurons within the nervous system. Recently the standard brain was complemented by the generation of a ventral nerve cord (VNC) standard. Here the authors have registered the major components of a simple neuronal circuit, the Giant Fiber System (GFS), into this standard. The authors show that they can also virtually reconstruct the well-characterized synaptic contact of the Giant Fiber with its motorneuronal target when they register the individual neurons from different preparations into the VNC standard. In addition to the potential application for the standard thorax in neuronal circuit reconstruction, the authors show that it is a useful tool for in-depth analysis of mutant morphology of single neurons. The authors find quantitative and qualitative differences when they compared the Giant Fibers of two different neuroglian alleles, nrg(849) and nrg(G00305), using the averaged wild-type GFS in the standard VNC as a reference.
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