Evidence map›Paper›PMID 20614991›Full record

ArticleJournal of biomedical optics

Multiphoton microscopy with near infrared contrast agents.

Siavash Yazdanfar, Chulmin Joo, Chun Zhan, Mikhail Y Berezin, Walter J Akers, Samuel Achilefu

Open access · bronzeAbstract readLetter
In one paragraph

Article in Journal of biomedical optics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Journal of biomedical optics · 2022
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Fluorescence lifetime imaging ophthalmoscopy.Progress in retinal and eye research · 2017
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Near-infrared molecular probes for in vivo imaging.Current protocols in cytometry · 2012
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Siavash Yazdanfar
Chulmin Joo
Chun Zhan
Mikhail Y Berezin
Walter J Akers
Samuel Achilefu
General Electric (United States) · USWashington University in St. Louis · US

Funding

NCI NIH HHS R21/R33 CA12353701
6 · The paper itself

Abstract

While multiphoton microscopy (MPM) has been performed with a wide range of excitation wavelengths, fluorescence emission has been limited to the visible spectrum. We introduce a paradigm for MPM of near-infrared (NIR) fluorescent molecular probes via nonlinear excitation at 1550 nm. This all-NIR system expands the range of available MPM fluorophores, virtually eliminates background autofluorescence, and allows for use of fiber-based, turnkey ultrafast lasers developed for telecommunications.

Indexed as

Cells, CulturedContrast MediaEpithelial CellsFluorescent DyesHumansImmunohistochemistryLasersMicroscopy, Fluorescence, MultiphotonNeoplasmsSpectroscopy, Near-InfraredContrast MediaFluorescent Dyes

Identifiers

PMID20614991
PMCPMC2881927
OpenAlexW2066380603

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.