Evidence map›Paper›PMID 20614428›Full record

SynthesisThe Cochrane database of systematic reviews2010

Behavioural treatment for chronic low-back pain.

Nicholas Henschke, Raymond Wjg Ostelo, Maurits W van Tulder, Johan Ws Vlaeyen, Stephen Morley, Willem Jj Assendelft, Chris J Main

Registry-linked trialOpen access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04023162 (Controlled, Randomized, Blind Trial Therapy Exercises and Operant Conditioning for Chronic Nonspecific Low Back Pain), which is not on this map. Cited by 167 papers, 29 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
167citing papers in PubMed, 29 pooled it
47.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04023162 nacompletednot on this mapstarted 2019, after this paper: background citation

Controlled, Randomized, Blind Trial Therapy Exercises and Operant Conditioning for Chronic Nonspecific Low Back Pain

TypeinterventionalSponsorAntonija HrkaćRan2019 to 2020Enrolled180ConditionsChronic Nonspecific Low Back PainArmsGraded Activity, Group-based Therapy Exercise, Back School
3 · Its place in the literature

Who cites it

167 citing papers in PubMed, 29 syntheses or guidelines pooled it, 714 citations in OpenAlex.

  1. Pooled it
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  5. Effectiveness of pharmacological and non-pharmacological therapy on pain intensity and disability in older people with chronic nonspecific low back pain: a systematic review with meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Pooled it
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  8. The Empirical Status of Mindfulness-Based Interventions: A Systematic Review of 44 Meta-Analyses of Randomized Controlled Trials.Perspectives on psychological science : a journal of the Association for Psychological Science · 2022
    Pooled it
  9. Exercise therapy for chronic low back pain.The Cochrane database of systematic reviews · 2021
    Pooled it
  10. The influence of cognitive behavioral therapy on lumbar spine surgery outcomes: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021
    Pooled it
  11. Epidural corticosteroid injections for lumbosacral radicular pain.The Cochrane database of systematic reviews · 2020
    Pooled it
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  17. Efficacy of Biofeedback in Chronic back Pain: a Meta-Analysis.International journal of behavioral medicine · 2017
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107 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 3 countries.

Nicholas HenschkeVU University Medical Centre, The George Institute for International Health, Sydney, Australia and EMGO+ Institute for Health and Care Research, van der Boechhorststraat 7, Amsterdam, North Holland, Netherlands, 1081 BT.
Raymond Wjg Ostelo
Maurits W van Tulder
Johan Ws Vlaeyen
Stephen Morley
Willem Jj Assendelft
Chris J Main
Amsterdam Public Health · NLAmsterdam UMC Location Vrije Universiteit Amsterdam · NLKeele University · GBLeiden University Medical Center · NLMaastricht University · NLThe George Institute for Global Health · AUUniversity of Leeds · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBehavioural treatment is commonly used in the management of chronic low-back pain (CLBP) to reduce disability through modification of maladaptive pain behaviours and cognitive processes. Three behavioural approaches are generally distinguished: operant, cognitive, and respondent; but are often combined as a treatment package.

objectivesTo determine the effects of behavioural therapy for CLBP and the most effective behavioural approach. SEARCH STRATEGY: The Cochrane Back Review Group Trials Register, CENTRAL, MEDLINE, EMBASE, and PsycINFO were searched up to February 2009. Reference lists and citations of identified trials and relevant systematic reviews were screened. SELECTION CRITERIA: Randomised trials on behavioural treatments for non-specific CLBP were included. DATA COLLECTION AND ANALYSIS: Two review authors independently assessed the risk of bias in each study and extracted the data. If sufficient homogeneity existed among studies in the pre-defined comparisons, a meta-analysis was performed. We determined the quality of the evidence for each comparison with the GRADE approach. MAIN

resultsWe included 30 randomised trials (3438 participants) in this review, up 11 from the previous version. Fourteen trials (47%) had low risk of bias. For most comparisons, there was only low or very low quality evidence to support the results. There was moderate quality evidence that:i) operant therapy was more effective than waiting list (SMD -0.43; 95%CI -0.75 to -0.11) for short-term pain relief;ii) little or no difference exists between operant, cognitive, or combined behavioural therapy for short- to intermediate-term pain relief;iii) behavioural treatment was more effective than usual care for short-term pain relief (MD -5.18; 95%CI -9.79 to -0.57), but there were no differences in the intermediate- to long-term, or on functional status;iv) there was little or no difference between behavioural treatment and group exercise for pain relief or depressive symptoms over the intermediate- to long-term;v) adding behavioural therapy to inpatient rehabilitation was no more effective than inpatient rehabilitation alone. AUTHORS'

conclusionsFor patients with CLBP, there is moderate quality evidence that in the short-term, operant therapy is more effective than waiting list and behavioural therapy is more effective than usual care for pain relief, but no specific type of behavioural therapy is more effective than another. In the intermediate- to long-term, there is little or no difference between behavioural therapy and group exercises for pain or depressive symptoms. Further research is likely to have an important impact on our confidence in the estimates of effect and may change the estimates.

Indexed as

Behavior TherapyChronic DiseaseConditioning, OperantDepressionHumansLow Back PainMuscle RelaxationRandomized Controlled Trials as TopicWaiting Lists

Identifiers

PMID20614428
PMCPMC7065591
OpenAlexW2117118000

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.