ReviewHead and neck pathology2008
Basaloid squamous cell carcinoma of the head and neck: a clinicopathological and follow-up study of 40 cases and review of the literature.
Review in Head and neck pathology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
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Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 98 citations in OpenAlex.
- Quantitative diffusion magnetic resonance imaging for prediction of human papillomavirus status in head and neck squamous-cell carcinoma: A systematic review and meta-analysis.The neuroradiology journal · 2019Pooled it
- Esophageal cancer: from pathogenesis to precision therapies.Signal transduction and targeted therapy · 2026Review
- Infrequent Histopathologic Subtypes of Oral Squamous Cell Carcinoma: A Case Series with Emphasis on Histopathologic Characteristics.Journal of dentistry (Shiraz, Iran) · 2025Article
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- Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Hypopharynx, Larynx, Trachea and Parapharyngeal Space.Head and neck pathology · 2022Review
- Transoral laryngeal microsurgery for early-stage laryngeal basaloid squamous cell carcinoma.BMJ case reports · 2021Article
- Malignant Sinonasal Tumors: Update on Histological and Clinical Management.Current oncology (Toronto, Ont.) · 2021Review
- CYLD mutation characterizes a subset of HPV-positive head and neck squamous cell carcinomas with distinctive genomics and frequent cylindroma-like histologic features.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2021Article
- Article
- Unusual Faces of Bladder Cancer.Cancers · 2020Review
- The importance of adjuvant treatment and primary anatomical site in head and neck basaloid squamous cell carcinoma survival: an analysis of the National Cancer Database.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2020Article
- Unusual Appearance of Basaloid SCC in Tonsil: A Case Report.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2019Article
- Endoscopic features and associated histology of an basaloid squamous cell carcinoma of the esophagus at the very early stage.BMC cancer · 2019Article
- A Rare Case of Stage IV Basaloid Squamous Cell Cancer with Intrapulmonary and Brain Metastases.The American journal of case reports · 2019Article
- Basaloid Squamous Cell Carcinoma of Tonsil: an Unusual and Aggressive Variant.Indian journal of surgical oncology · 2019Article
- Sponge-supported cultures of primary head and neck tumors for an optimized preclinical model.Oncotarget · 2018Article
- Cause-specific mortality prediction model for patients with basaloid squamous cell carcinomas of the head and neck: a competing risk analysis.Journal of Cancer · 2018Article
- Aggressiveness pattern and second primary tumor risk associated with basaloid squamous cell carcinoma of the larynx.Oncotarget · 2017Article
- Basaloid Squamous Cell Carcinoma of Tongue: A Report with Emphasis on Immunohistochemistry.Journal of clinical and diagnostic research : JCDR · 2017Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Basaloid squamous cell carcinoma (BSCC) is a rare and aggressive variant of cancer that mainly arises in the upper aerodigestive tract. This study reviews the clinico-pathological features and follow-up of a series of cases occurring in the head and neck. During a 32-year period (1974-2005), a total of 40 BSCCs have been diagnosed in the head and neck in our Institution. Males predominated in the series (35M/5F). The average age was 60.2 years (range, 40-85). Tobacco and alcohol consumption was found in more than 80% of the cases. Topographic distribution was as follows: larynx and hypopharynx, 22 cases (55%); oropharynx, 12 cases (30%); and oral cavity 6 cases (15%). The basaloid component predominated in 29 cases (72.5%). Vasculo-lymphatic invasion was detected in 5 cases (12.5%). Lymph node metastases were seen in 25 cases (62.5%, levels II and III in the neck dissection). Local recurrences appeared in 11 cases (27.5%) and distant metastases in 6 (15%). In 7 cases (17.5%) a second primary tumour was detected. The 2002 TNM staging was as follows: Stage I, 5 cases (12.5%); Stage II, 7 cases (17.5%); Stage III, 8 cases (20%), and Stage IV, 20 cases (50%). On follow-up, 21 cases (52.5%) are alive and 19 (47.5%) died of disease. Three- and 5-year overall survival was 50% and 38.5%, respectively. A significant shorter survival was detected in node positive patients (P<0.05).
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