ArticleHead and neck pathology2007
Translocation t(6;14) as the sole chromosomal abnormality in adenoid cystic carcinoma of the base of tongue.
Article in Head and neck pathology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Chromosomal abnormalities and molecular landscape of metastasizing mucinous salivary adenocarcinoma.Oral oncology · 2017Article
- Development and characterization of salivary adenoid cystic carcinoma cell line.Oral oncology · 2014Article
- Novel chromosomal rearrangements and break points at the t(6;9) in salivary adenoid cystic carcinoma: association with MYB-NFIB chimeric fusion, MYB expression, and clinical outcome.Clinical cancer research : an official journal of the American Association for Cancer Research · 2011Article
- Comprehensive analysis of the MYB-NFIB gene fusion in salivary adenoid cystic carcinoma: Incidence, variability, and clinicopathologic significance.Clinical cancer research : an official journal of the American Association for Cancer Research · 2010Article
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Authors and funding
5 authors.
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Abstract
We present an adenoid cystic carcinoma of the base of tongue in a 48-year-old male with a restricted chromosomal alteration by cytogenetic and spectral karyotypic analysis (SKY). SKY and G-banding analyses identified the t(6;14)(q25;q13) as the sole structural aberration in all metaphases analyzed. This finding supports a critical role for this event in the development of this tumor. The implications of chromosome 6q translocation in this case and in previously reported adenoid cystic carcinomas are highlighted and discussed.
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