ArticleClinics (Sao Paulo, Brazil)2010
Norepinephrine remains increased in the six-minute walking test after heart transplantation.
Article in Clinics (Sao Paulo, Brazil), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 22 citations in OpenAlex.
- Sympathetic Reinnervation of Intact and Upper Follicle Xenografts into BALB/c-nu/nu Mice.Life (Basel, Switzerland) · 2023Article
- Double Product and Autonomic Function as Predictors of Quality of Life in Heart Transplant Recipients: A Cross-Sectional Study.Brazilian journal of cardiovascular surgery · 2022Article
- Early Denervation and Later Reinnervation of the Heart Following Cardiac Transplantation: A Review.Journal of the American Heart Association · 2016Review
- Exercise and its interactions with various aspects of man and animal lives.Acta ortopedica brasileira · 2012Article
- Prognostic value of the six-minute walk test in end-stage renal disease life expectancy: a prospective cohort study.Clinics (Sao Paulo, Brazil) · 2012Article
- Predictors of low cardiac output in decompensated severe heart failure.Clinics (Sao Paulo, Brazil) · 2011Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe sought to evaluate the neurohormonal activity in heart transplant recipients and compare it with that in heart failure patients and healthy subjects during rest and just after a 6-minute walking test.
introductionDespite the improvements in quality of life and survival provided by heart transplantation, the neurohormonal profile is poorly described.
methodsTwenty heart transplantation (18 men, 49+/-11 years and 8.5+/-3.3 years after transplantation), 11 heart failure (8 men, 43+/-10 years), and 7 healthy subjects (5 men 39+/-8 years) were included in this study. Blood samples were collected immediately before and during the last minute of the exercise.
resultsDuring rest, patients' norepinephrine plasma level (659+/-225 pg/mL) was higher in heart transplant recipients (463+/-167 pg/mL) and healthy subjects (512+/-132), p<0.05. Heart transplant recipient's norepinephrine plasma level was not different than that of healthy subjects. Just after the 6-minute walking test, the heart transplant recipient's norepinephrine plasma level (1248+/-692 pg/mL) was not different from that of heart failure patients (1174+/-653 pg/mL). Both these groups had a higher level than healthy subjects had (545+/-95 pg/mL), p<0.05.
conclusionNeurohormonal activity remains increased after the 6-minute walking test after heart transplantation.
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