Evidence map›Paper›PMID 20613544›Full record

ArticleGenetics in medicine : official journal of the American College of Medical Genetics2010

African Americans' responses to genetic explanations of lung cancer disparities and their willingness to participate in clinical genetics research.

Della Brown White, Laura M Koehly, Adedamola Omogbehin, Colleen M McBride

Open access · bronzeAbstract read
In one paragraph

Article in Genetics in medicine : official journal of the American College of Medical Genetics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Beliefs and Preferences for Medical Research Among African-Americans.Journal of racial and ethnic health disparities · 2016
    Article
  5. Strategies for enrollment of African Americans into cancer genetic studies.Journal of cancer education : the official journal of the American Association for Cancer Education · 2015
    Article
  6. Article
  7. Advancing genomic research and reducing health disparities: what can nurse scholars do?Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2013
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Della Brown WhiteSocial and Behavioral Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892-2073, USA. whitede@mail.nih.gov
Laura M Koehly
Adedamola Omogbehin
Colleen M McBride
National Human Genome Research Institute · USMedStar Washington Hospital Center · USNational Institutes of Health · US

Funding

Family Risk and Lung Cancer StudyZ01HG200315 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI MC BRIDE, COLLEEN M · 2004 to 2008
$2.1M
Intramural NIH HHS Z01 HG200315
6 · The paper itself

Abstract

purposeTo assess whether reactions to genetic explanations for disparities in lung cancer incidence among family members of African American patients with lung cancer are associated with willingness to participate in clinical genetics research.

methodsData are reported for 67 self-identified African Americans aged 18 to 55 years who completed a telephone survey assessing reactions to explanations (i.e., genetics, toxin exposure, menthol cigarettes, and race-related stress) for lung cancer disparities. Majority were female (70%), current smokers (57%), and patients' biological relatives (70%).

resultsFamily members rated the four explanations similarly, each as believable, fair, and not too worrisome. Participants also indicated a high level of willingness to participate in genetics research (M = 4.1 +/- 1.0; scale: 1-5). Endorsements of genetics explanations for disparities as believable and fair, and toxin exposure as believable were associated significantly with willingness to participate in genetics research.

conclusionThese results suggest that strategies to encourage African Americans' participation in genetics research would do well to inform potential participants of how their involvement might be used to better understand important environmental factors that affect health disparities.

Indexed as

AdultBlack or African AmericanControlled Clinical Trials as TopicDistrict of ColumbiaFemaleGenetic CounselingHumansInterviews as TopicLung NeoplasmsMaleMiddle AgedPatient ParticipationRisk FactorsSmoking

Identifiers

PMID20613544
PMCPMC3518377
OpenAlexW2011911034

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.