ReviewCurrent opinion in organ transplantation2010
Alloimmunity and autoimmunity in chronic rejection.
Review in Current opinion in organ transplantation, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 41 citations in OpenAlex.
- Perspective view of allogeneic IgG tumor immunotherapy.Cancer cell international · 2024Review
- Hashimoto's thyroiditis and renal transplant rejection.Journal of endocrinological investigation · 2023Article
- A cofunctional grouping-based approach for non-redundant feature gene selection in unannotated single-cell RNA-seq analysis.Briefings in bioinformatics · 2023Article
- Chronic lung allograft pathology lesions in two rat strain combinations.Journal of thoracic disease · 2021Article
- Zbtb7a induction in alveolar macrophages is implicated in anti-HLA-mediated lung allograft rejection.Science translational medicine · 2017Article
- Autologous subcutaneous adipose tissue transplants improve adipose tissue metabolism and reduce insulin resistance and fatty liver in diet-induced obesity rats.Physiological reports · 2016Article
- Autologous and Allogenous Antibodies in Lung and Islet Cell Transplantation.Frontiers in immunology · 2016Review
- "Mouse Clone Model" for evaluating the immunogenicity and tumorigenicity of pluripotent stem cells.Stem cell research & therapy · 2015Article
- Facial and hand allotransplantation.Cold Spring Harbor perspectives in medicine · 2014Review
- Decellularized matrices for cardiovascular tissue engineering.American journal of stem cells · 2014Review
- Anti-major histocompatibility complex-induced obliterative airway disease: selective role for CD4 and CD8 T cells in inducing immune responses to self-antigens.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2013Article
- B-lymphocyte lineage cells and the respiratory system.The Journal of allergy and clinical immunology · 2013Review
- Complement activation is not required for obliterative airway disease induced by antibodies to major histocompatibility complex class I: Implications for chronic lung rejection.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2012Article
- T regulatory cells play a significant role in modulating MHC class I antibody-induced obliterative airway disease.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2012Article
- Chronic rejection: a significant role for Th17-mediated autoimmune responses to self-antigens.Expert review of clinical immunology · 2012Review
- IDO-competent-DCs induced by IFN-γ attenuate acute rejection in rat liver transplantation.Journal of clinical immunology · 2012Article
- Inhibition of renin angiotensin aldosterone system causes abrogation of obliterative airways disease through inhibition of tumor necrosis factor-α-dependant interleukin-17.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2012Article
- A shift in the collagen V antigenic epitope leads to T helper phenotype switch and immune response to self-antigen leading to chronic lung allograft rejection.Clinical and experimental immunology · 2012Article
- Article
- Immunologic basis of graft rejection and tolerance following transplantation of liver or other solid organs.Gastroenterology · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
purpose of reviewRecent studies demonstrate an increasing role for alloimmune responses in the disruption of self-tolerance leading to immune responses to self-antigens that play a role in the immunopathogenesis of chronic rejection following solid organ transplantation. This review summarizes recent studies and implications for the alloimmune-response-induced de-novo development of autoimmune responses following solid organ transplantations. RECENT
findingsImmediately following organ transplantation, several factors lead to enduring an inflammatory milieu. Studies from our laboratory and others have demonstrated that development of antihuman leukocyte antigen antibodies precedes the development of chronic rejection. Using an in-vivo murine model, we have demonstrated that administration of anti-major histocompatibility complex (MHC) class I directly into the native lungs leads to chronic rejection pathology. Further, the in-vitro ligation of epithelial cell surface MHC class I molecules by specific anti-MHC can lead to cell activation and production of fibrinogenic growth factors. SUMMARY: On the basis of these findings, we hypothesized that alloimmune responses can lead to autoimmunity, thus playing an important role in chronic rejection. Characterization of both the temporal occurrence and functional significance of antibodies to self-antigens may provide insight into the pathogenesis of chronic rejection and these antibodies can serve as clinically useful biomarkers.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.