ArticleAIDS (London, England)2010
Association between HLA inheritance and asthma medication use in HIV positive children.
Article in AIDS (London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Immune imbalance and activation are associated with lower lung function in youth with perinatally acquired HIV.The Journal of allergy and clinical immunology · 2020Article
- Long-term pulmonary complications in perinatally HIV-infected youth.The Journal of allergy and clinical immunology · 2017Article
- Bronchiectasis and other chronic lung diseases in adolescents living with HIV.Current opinion in infectious diseases · 2017Review
- Associations of cytokines, sleep patterns, and neurocognitive function in youth with HIV infection.Clinical immunology (Orlando, Fla.) · 2012Article
- High prevalence of asthma in HIV-infected adults: new insights.The Journal of allergy and clinical immunology · 2012Article
- Increased risk of asthma and atopic dermatitis in perinatally HIV-infected children and adolescents.Clinical immunology (Orlando, Fla.) · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
This study's purpose was to determine whether asthma medication use in HIV positive children is associated with human leukocyte antigen (HLA) alleles. We reviewed HLA and medication data collected during the Women and Infants Transmission Study for 124 HIV positive children and their mothers. Analysis revealed that HLA-A68 (P = 0.006) was independent and predictive for time to first asthma medication use. There was a preventive association of Cw6 (P = 0.008) with asthma time. Highly active antiretroviral therapy (HAART) was also associated with time to first asthma medication use (P = 0.05). HLA alleles may modulate risk of developing a need for asthma medications and seem to function independently of the actions of HAART therapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.