Evidence map›Paper›PMID 20610688›Full record

ArticleJournal of clinical microbiology2010

Laboratory surveillance for prospective plasmid-mediated AmpC beta-lactamases in the Kinki region of Japan.

Katsutoshi Yamasaki, Masaru Komatsu, Noriyuki Abe, Saori Fukuda, Yugo Miyamoto, Takeshi Higuchi, Tamotsu Ono, Hisaaki Nishio, Noriyuki Sueyoshi, Kaneyuki Kida and 14 more

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Recurrence ofIDCases · 2017
    Article
  7. Article
  8. Bloodstream infections caused by Escherichia coli producing AmpC β-lactamases: epidemiology and clinical features.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2016
    Article
  9. Emergence of CMY-2- and DHA-1-type AmpC β-lactamases inIranian journal of microbiology · 2016
    Article
  10. Article
  11. Article
  12. Long-term dissemination of acquired AmpC β-lactamases among Klebsiella spp. and Escherichia coli in Portuguese clinical settings.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2014
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Prevalence and molecular epidemiology of acquired AmpC β-lactamases and carbapenemases in Enterobacteriaceae isolates from 35 hospitals in Spain.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2013
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Katsutoshi YamasakiDepartment of Clinical Laboratory, Wakayama Rosai Hospital, 93-1 Kinomoto, Wakayama City, Wakayama 640-8505, Japan. ktt-yamazaki@wakayamah.rofuku.go.jp
Masaru Komatsu
Noriyuki Abe
Saori Fukuda
Yugo Miyamoto
Takeshi Higuchi
Tamotsu Ono
Hisaaki Nishio
Noriyuki Sueyoshi
Kaneyuki Kida
Kaori Satoh
Masahiro Toyokawa
Isao Nishi
Masako Sakamoto
Masahiro Akagi
Isako Nakai
Tomomi Kofuku
Tamaki Orita
Yasunao Wada
Takumi Jikimoto
Shohiro Kinoshita
Kazuaki Miyamoto
Itaru Hirai
Yoshimasa Yamamoto

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extended-spectrum beta-lactamases, plasmid-mediated AmpC beta-lactamases (PABLs), and plasmid-mediated metallo-beta-lactamases confer resistance to many beta-lactams. In Japan, although several reports exist on the prevalence of extended-spectrum beta-lactamases and metallo-beta-lactamases, the prevalence and characteristics of PABLs remain unknown. To investigate the production of PABLs, a total of 22,869 strains of 4 enterobacterial species, Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, and Proteus mirabilis, were collected during six 6-month periods from 17 clinical laboratories in the Kinki region of Japan. PABLs were detected in 29 (0.13%) of 22,869 isolates by the 3-dimensional test, PCR analysis, and DNA sequencing analysis. PABL-positive isolates were detected among isolates from 13 laboratories. Seventeen of 13,995 (0.12%) E. coli isolates, 8 of 5,970 (0.13%) K. pneumoniae isolates, 3 of 1,722 (0.17%) K. oxytoca isolates, and 1 of 1,182 (0.08%) P. mirabilis isolates were positive for PABLs. Of these 29 PABL-positive strains, 20 (69.0%), 6 (20.7%), 2 (6.9%), and 1 (3.4%) carried the genes for CMY-2, DHA-1, CMY-8, and MOX-1 PABLs, respectively. Pattern analysis of randomly amplified polymorphic DNA and pulsed-field gel electrophoretic analysis revealed that the prevalence of CMY-2-producing E. coli strains was not due to epidemic strains and that 3 DHA-1-producing K. pneumoniae strains were identical, suggesting their clonal relatedness. In conclusion, the DHA-1 PABLs were predominantly present in K. pneumoniae strains, but CMY-2 PABLs were predominantly present in E. coli strains. The present findings will provide significant information to assist in preventing the emergence and further spread of PABL-producing bacteria.

Indexed as

Anti-Bacterial AgentsBacterial ProteinsBacterial Typing Techniquesbeta-Lactamasesbeta-LactamsDNA, BacterialDNA FingerprintingElectrophoresis, Gel, Pulsed-FieldEnterobacteriaceae InfectionsEscherichia coliHumansJapanKlebsiellaMicrobial Sensitivity TestsMolecular EpidemiologyPlasmidsAmpC beta-lactamasesAnti-Bacterial AgentsBacterial Proteinsbeta-Lactamasesbeta-LactamsDNA, Bacterial

Identifiers

PMID20610688
PMCPMC2937711

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.