ArticleGenetics2010
A strategy for direct mapping and identification of mutations by whole-genome sequencing.
Article in Genetics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers.
What it found
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Who cites it
101 citing papers in PubMed.
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- Worm orthologues of cytokinesis-associated proteins CIT and ASPM regulate neuronal microtubule dynamics and polarity in C. elegans.PLoS genetics · 2026Article
- Molecular Determinants of TMC Protein Biogenesis and Trafficking.International journal of molecular sciences · 2025Article
- Configuration of electrical synapses filters sensory information to drive behavioral choices.Cell · 2025Article
- OSP-1 protects neurons from autophagic cell death induced by acute oxidative stress.Nature communications · 2025Article
- Essential and dual effects of Notch activity on a natural transdifferentiation event.Nature communications · 2025Article
- Protocol for forward genetic screening to identify novel factors involved in a biological process in Caenorhabditis elegans.STAR protocols · 2024Article
- The ACE inhibitor captopril inhibits ACN-1 to control dauer formation and aging.Development (Cambridge, England) · 2024Article
- Distinct pathways for export of silencing RNA iniScience · 2023Article
- Wheat Water-Soluble Carbohydrate Remobilisation under Water Deficit byCurrent issues in molecular biology · 2023Article
- Article
- Versatile mapping-by-sequencing with Easymap v.2.Frontiers in plant science · 2023Article
- A natural transdifferentiation event involving mitosis is empowered by integrating signaling inputs with conserved plasticity factors.Cell reports · 2022Article
- Translational relevance of forward genetic screens in animal models for the study of psychiatric disease.Neuroscience and biobehavioral reviews · 2022Review
- Impairing one sensory modality enhances another by reconfiguring peptidergic signalling ineLife · 2022Article
- The redundancy and diversity between two novel PKC isotypes that regulate learning inProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Mutation Mapping and Identification by Whole-Genome Sequencing.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Identification of essential genes in Caenorhabditis elegans through whole-genome sequencing of legacy mutant collections.G3 (Bethesda, Md.) · 2021Article
41 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mutant screens have proven powerful for genetic dissection of a myriad of biological processes, but subsequent identification and isolation of the causative mutations are usually complex and time consuming. We have made the process easier by establishing a novel strategy that employs whole-genome sequencing to simultaneously map and identify mutations without the need for any prior genetic mapping.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.